| UniProt/SwissProt ID: | ACL6B_HUMAN |
| Description: | actin-like 6B [Source:HGNC Symbol;Acc:160] |
| Location: | chr7 q22.1 |
| Node attribute: | substrate |
| Phosphorylation site |
| Position | PhosphoPeptide | Catalytic kinase | Source |
|---|---|---|---|
| Y104 | ILDHTySKHVK | Actin | PhosphoSitePlus |
| S244 | KLPQVsKSWHN | HPRD | |
| S244 | KLPQVsKSWHN | Actin | PhosphoSitePlus |
| Dephosphorylation site |
| ACL6B_HUMAN do not have dephosphorylation site. |
| Mutation site |
| Ensembl ID | Variation | Source | Cancer name | Pubmed |
|---|---|---|---|---|
| ENSP00000160382 | E385* | COSMIC | Ovarian Cancer | 21720365 | ENSP00000160382 | G78E | COSMIC | Skin Cancer | 21984974 |
| Differential expressed protein |
| ACL6B_HUMAN is not differential expressed protein. |
| Hyperphosphorylation site |
| ACL6B_HUMAN do not have hyperphosphorylation site. |
| Direct Interaction Pair |
| Source | Target | Relationship | Resource |
|---|---|---|---|
| CDKL5_HUMAN | ACL6B_HUMAN | kinase -> substrate | Robert H Newman (2013) |
| Function Annotation |
| KEGG Pathway |
| ACL6B_HUMAN is not in KEGG pathway. |
| Gene Ontology |
| GO ID | GO_Term | Evidence | Ontology |
|---|---|---|---|
| GO:0071565 | nBAF complex | IEA | cellular_component |
| GO:0005634 | nucleus | IDA | cellular_component |
| GO:0003713 | transcription coactivator activity | NAS | molecular_function |
| GO:0006351 | transcription, DNA-dependent | IEA | biological_process |
| GO:0006325 | chromatin organization | NAS | biological_process |
| GO:0006338 | chromatin remodeling | IDA | biological_process |
| GO:0005200 | structural constituent of cytoskeleton | TAS | molecular_function |
| GO:0005730 | nucleolus | IDA | cellular_component |
| GO:0016514 | SWI/SNF complex | IEA | cellular_component |
| GO:0005524 | ATP binding | IEA | molecular_function |
| GO:0006357 | regulation of transcription from RNA polymerase II | NAS | biological_process |
| GO:0007399 | nervous system development | IEA | biological_process |