Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:TRIP4_HUMAN
Description:thyroid hormone receptor interactor 4 [Source:HGNC Symbol;Acc:12310]
Location:chr15 q22.31
Node attribute:substrate

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
S406KKAFRsSGFGLHPRD
S341LEEENsLAEYHPhosphoSitePlus
T280TSIRRtQVIDDPhosphoSitePlus
S482SPQEVsELQATPhosphoSitePlus
Y153KFVNLyTREGQPhosphoSitePlus
Y345NSLAEyHSRLDPhosphoSitePlus
S237SGVENsGKVDIPhosphoSitePlus
S477TAKKPsPQEVSPhosphoSitePlus
T154FVNLYtREGQDPhosphoSitePlus
S387PNMYQsPPQWVPhosphoSitePlus
S287VIDDEsDYFASPhosphoSitePlus
Y289DDESDyFASDSPhosphoSitePlus; HPRD; phosphoELM
T209GTLVCtHEEQDzf-C2HC5PhosphoSitePlus
Y385VNPNMyQSPPQPhosphoSitePlus; HPRD; phosphoELM
S371TKLDRsSEEPLPhosphoSitePlus

Dephosphorylation site
TRIP4_HUMAN do not have dephosphorylation site.

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000261884G238ECOSMICHead and Neck Cancer21984974
ENSP00000261884R421*COSMICRenal Cancer20054297
ENSP00000261884E302QBIOMARTHepatocellular Carcinoma21930507, 21930502
ENSP00000261884V127LCOSMICMelanoma21499247

Differential expressed protein
TRIP4_HUMAN is not differential expressed protein.

Hyperphosphorylation site
TRIP4_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
KS6A2_HUMANTRIP4_HUMANkinase -> substrateRobert H Newman (2013)
STK11_HUMANTRIP4_HUMANkinase -> substrateRobert H Newman (2013)

Function Annotation
KEGG Pathway
TRIP4_HUMAN is not in KEGG pathway.

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0005737cytoplasmIDAcellular_component
GO:0008270zinc ion bindingIEAmolecular_function
GO:0016922ligand-dependent nuclear receptor bindingIDAmolecular_function
GO:0006366transcription from RNA polymerase II promoterTASbiological_process
GO:0003713transcription coactivator activityTASmolecular_function
GO:0005634nucleusIDAcellular_component
GO:0006355regulation of transcription, DNA-dependentIEAbiological_process
GO:0005815microtubule organizing centerIEAcellular_component
GO:0045893positive regulation of transcription, DNA-dependenNASbiological_process


Fatal error: Uncaught Error: Call to undefined function mysql_close() in /usr/local/apache/htdocs/PhoSigNet/include/locateconfig.inc.php:23 Stack trace: #0 /usr/local/apache/htdocs/PhoSigNet/proteintable.php(435): db_disconnect(Object(mysqli)) #1 {main} thrown in /usr/local/apache/htdocs/PhoSigNet/include/locateconfig.inc.php on line 23