| UniProt/SwissProt ID: | TOB2_HUMAN |
| Description: | transducer of ERBB2, 2 [Source:HGNC Symbol;Acc:11980] |
| Location: | chr22 q13.2 |
| Node attribute: | substrate |
| Phosphorylation site |
| Position | PhosphoPeptide | Catalytic kinase | Source |
|---|---|---|---|
| S155 | LSNSPsPSFGQ | PhosphoSitePlus | |
| S254 | PQSQLsPNAKE | PAM2 | PhosphoSitePlus |
| T244 | SLNFItANPAP | PhosphoSitePlus | |
| S163 | FGQSPsPTFIP | PhosphoSitePlus | |
| T317 | LFLEKtPFVEG | PhosphoSitePlus | |
| Y40 | LLKKKyEGHWY | BTG | PhosphoSitePlus |
| S153 | SSLSNsPSPSF | PhosphoSitePlus | |
| Dephosphorylation site |
| TOB2_HUMAN do not have dephosphorylation site. |
| Mutation site |
| TOB2_HUMAN do not have mutation site. |
| Differential expressed protein |
| TOB2_HUMAN is not differential expressed protein. |
| Hyperphosphorylation site |
| TOB2_HUMAN do not have hyperphosphorylation site. |
| Direct Interaction Pair |
| Source | Target | Relationship | Resource |
|---|---|---|---|
| HIPK4_HUMAN | TOB2_HUMAN | kinase -> substrate | Robert H Newman (2013) |
| Function Annotation |
| KEGG Pathway |
| TOB2_HUMAN is not in KEGG pathway. |
| Gene Ontology |
| GO ID | GO_Term | Evidence | Ontology |
|---|---|---|---|
| GO:0007292 | female gamete generation | TAS | biological_process |
| GO:0042809 | vitamin D receptor binding | IEA | molecular_function |
| GO:0045778 | positive regulation of ossification | IEA | biological_process |
| GO:0005737 | cytoplasm | IEA | cellular_component |
| GO:0005634 | nucleus | TAS | cellular_component |
| GO:0045671 | negative regulation of osteoclast differentiation | IEA | biological_process |
| GO:0008285 | negative regulation of cell proliferation | TAS | biological_process |
| GO:0010468 | regulation of gene expression | IEA | biological_process |