| UniProt/SwissProt ID: | TNR25_HUMAN |
| Description: | tumor necrosis factor receptor superfamily, member 25 [Source:HGNC Symbol;Acc:11910] |
| Location: | chr1 p36.31 |
| Node attribute: | receptor |
| Phosphorylation site |
| TNR25_HUMAN do not have phosphorylation site. |
| Dephosphorylation site |
| TNR25_HUMAN do not have dephosphorylation site. |
| Mutation site |
| Ensembl ID | Variation | Source | Cancer name | Pubmed |
|---|---|---|---|---|
| ENSP00000367013 | E124* | COSMIC | Breast Cancer | 16959974 | ENSP00000367013 | R158K | COSMIC | Central Nervous System Neoplasms | 18772890 | ENSP00000349341 | E124X | BIOMART | Breast Cancer | 21930507, 21930502 |
| Differential expressed protein |
| TNR25_HUMAN is not differential expressed protein. |
| Hyperphosphorylation site |
| TNR25_HUMAN do not have hyperphosphorylation site. |
| Direct Interaction Pair |
| Source | Target | Relationship | Resource |
|---|---|---|---|
| TNF15_HUMAN | TNR25_HUMAN | ligand -> receptor | HPMR |
| Function Annotation |
| KEGG Pathway |
| KEGG ID | Pathway |
|---|---|
| hsa04060 | Cytokine-cytokine receptor interaction |
| Gene Ontology |
| GO ID | GO_Term | Evidence | Ontology |
|---|---|---|---|
| GO:0006917 | induction of apoptosis | TAS | biological_process |
| GO:0005576 | extracellular region | IEA | cellular_component |
| GO:0042981 | regulation of apoptotic process | NAS | biological_process |
| GO:0033209 | tumor necrosis factor-mediated signaling pathway | TAS | biological_process |
| GO:0097190 | apoptotic signaling pathway | TAS | biological_process |
| GO:0005829 | cytosol | NAS | cellular_component |
| GO:0005515 | protein binding | IEA | molecular_function |
| GO:0005887 | integral to plasma membrane | TAS | cellular_component |
| GO:0006915 | apoptotic process | NAS | biological_process |
| GO:0005031 | tumor necrosis factor-activated receptor activity | TAS | molecular_function |
| GO:0004872 | receptor activity | NAS | molecular_function |
| GO:0007165 | signal transduction | TAS | biological_process |
| GO:0005886 | plasma membrane | IDA | cellular_component |
| GO:0007166 | cell surface receptor signaling pathway | TAS | biological_process |