UniProt/SwissProt ID: | TNR12_HUMAN |
Description: | tumor necrosis factor receptor superfamily, member 12A [Source:HGNC Symbol;Acc:18152] |
Location: | chr16 p13.3 |
Node attribute: | receptor; PPI(target) |
Phosphorylation site |
TNR12_HUMAN do not have phosphorylation site. |
Dephosphorylation site |
TNR12_HUMAN do not have dephosphorylation site. |
Mutation site |
Ensembl ID | Variation | Source | Cancer name | Pubmed |
---|---|---|---|---|
ENSP00000326737 | R107K | COSMIC | Skin Cancer | 21984974 |
Differential expressed protein |
Ensembl ID | Cancer name | Design | Sample | Change | Ratio | Pubmed |
---|---|---|---|---|---|---|
ENSP00000326737 | Testicular Cancer | Normal vs. Cancer | cell line | Down | 18489135 | |
Hyperphosphorylation site |
TNR12_HUMAN do not have hyperphosphorylation site. |
Direct Interaction Pair |
Source | Target | Relationship | Resource |
---|---|---|---|
TNF12_HUMAN | TNR12_HUMAN | ligand -> receptor | HPMR |
TNF12_HUMAN | TNR12_HUMAN | other | KEGG |
Function Annotation |
KEGG Pathway |
KEGG ID | Pathway |
---|---|
hsa04060 | Cytokine-cytokine receptor interaction |
Gene Ontology |
GO ID | GO_Term | Evidence | Ontology |
---|---|---|---|
GO:0045773 | positive regulation of axon extension | IEA | biological_process |
GO:0008219 | cell death | IEA | biological_process |
GO:0006931 | substrate-dependent cell migration, cell attachmen | IEA | biological_process |
GO:0001525 | angiogenesis | IEA | biological_process |
GO:2001238 | positive regulation of extrinsic apoptotic signali | IMP | biological_process |
GO:0006928 | cellular component movement | TAS | biological_process |
GO:0007275 | multicellular organismal development | TAS | biological_process |
GO:0005886 | plasma membrane | IEA | cellular_component |
GO:0009986 | cell surface | IEA | cellular_component |
GO:0016021 | integral to membrane | IEA | cellular_component |
GO:0001726 | ruffle | IEA | cellular_component |
GO:0006915 | apoptotic process | IEA | biological_process |
GO:0006917 | induction of apoptosis | IDA | biological_process |
GO:0005515 | protein binding | IEA | molecular_function |
GO:0007155 | cell adhesion | IEA | biological_process |
GO:0005515 | protein binding | IPI | molecular_function |