| UniProt/SwissProt ID: | TNR12_HUMAN |
| Description: | tumor necrosis factor receptor superfamily, member 12A [Source:HGNC Symbol;Acc:18152] |
| Location: | chr16 p13.3 |
| Node attribute: | receptor; PPI(target) |
| Phosphorylation site |
| TNR12_HUMAN do not have phosphorylation site. |
| Dephosphorylation site |
| TNR12_HUMAN do not have dephosphorylation site. |
| Mutation site |
| Ensembl ID | Variation | Source | Cancer name | Pubmed |
|---|---|---|---|---|
| ENSP00000326737 | R107K | COSMIC | Skin Cancer | 21984974 |
| Differential expressed protein |
| Ensembl ID | Cancer name | Design | Sample | Change | Ratio | Pubmed |
|---|---|---|---|---|---|---|
| ENSP00000326737 | Testicular Cancer | Normal vs. Cancer | cell line | Down | 18489135 | |
| Hyperphosphorylation site |
| TNR12_HUMAN do not have hyperphosphorylation site. |
| Direct Interaction Pair |
| Source | Target | Relationship | Resource |
|---|---|---|---|
| TNF12_HUMAN | TNR12_HUMAN | ligand -> receptor | HPMR |
| TNF12_HUMAN | TNR12_HUMAN | other | KEGG |
| Function Annotation |
| KEGG Pathway |
| KEGG ID | Pathway |
|---|---|
| hsa04060 | Cytokine-cytokine receptor interaction |
| Gene Ontology |
| GO ID | GO_Term | Evidence | Ontology |
|---|---|---|---|
| GO:0045773 | positive regulation of axon extension | IEA | biological_process |
| GO:0008219 | cell death | IEA | biological_process |
| GO:0006931 | substrate-dependent cell migration, cell attachmen | IEA | biological_process |
| GO:0001525 | angiogenesis | IEA | biological_process |
| GO:2001238 | positive regulation of extrinsic apoptotic signali | IMP | biological_process |
| GO:0006928 | cellular component movement | TAS | biological_process |
| GO:0007275 | multicellular organismal development | TAS | biological_process |
| GO:0005886 | plasma membrane | IEA | cellular_component |
| GO:0009986 | cell surface | IEA | cellular_component |
| GO:0016021 | integral to membrane | IEA | cellular_component |
| GO:0001726 | ruffle | IEA | cellular_component |
| GO:0006915 | apoptotic process | IEA | biological_process |
| GO:0006917 | induction of apoptosis | IDA | biological_process |
| GO:0005515 | protein binding | IEA | molecular_function |
| GO:0007155 | cell adhesion | IEA | biological_process |
| GO:0005515 | protein binding | IPI | molecular_function |