Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:TNFL4_HUMAN
Description:tumor necrosis factor (ligand) superfamily, member 4 [Source:HGNC Symbol;Acc:11934]
Location:chr1 q25.1
Node attribute:ligand; PPI(source)

Phosphorylation site
TNFL4_HUMAN do not have phosphorylation site.

Dephosphorylation site
TNFL4_HUMAN do not have dephosphorylation site.

Mutation site
TNFL4_HUMAN do not have mutation site.

Differential expressed protein
TNFL4_HUMAN is not differential expressed protein.

Hyperphosphorylation site
TNFL4_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
TNFL4_HUMANTNR4_HUMANligand -> receptorHPMR
TNFL4_HUMANTNR4_HUMANotherKEGG

Function Annotation
KEGG Pathway
KEGG IDPathway
hsa04060Cytokine-cytokine receptor interaction

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0035712T-helper 2 cell activationIEAbiological_process
GO:0005164tumor necrosis factor receptor bindingIEAmolecular_function
GO:0071954chemokine (C-C motif) ligand 11 productionIEAbiological_process
GO:0045590negative regulation of regulatory T cell differentIEAbiological_process
GO:1900281positive regulation of CD4-positive, alpha beta T IEAbiological_process
GO:0006955immune responseIEAbiological_process
GO:0045892negative regulation of transcription, DNA-dependenIEAbiological_process
GO:0042098T cell proliferationIEAbiological_process
GO:0035708interleukin-4-dependent isotype switching to IgE iIEAbiological_process
GO:0032735positive regulation of interleukin-12 productionISSbiological_process
GO:0002819regulation of adaptive immune responseIEAbiological_process
GO:0032736positive regulation of interleukin-13 productionISSbiological_process
GO:0032733positive regulation of interleukin-10 productionISSbiological_process
GO:0043382positive regulation of memory T cell differentiatiISSbiological_process
GO:0005102receptor bindingTASmolecular_function
GO:0051024positive regulation of immunoglobulin secretionIEAbiological_process
GO:0032736positive regulation of interleukin-13 productionIEAbiological_process
GO:0050727regulation of inflammatory responseISSbiological_process
GO:0035709memory T cell activationISSbiological_process
GO:0032700negative regulation of interleukin-17 productionIDAbiological_process
GO:0002891positive regulation of immunoglobulin mediated immISSbiological_process
GO:0043433negative regulation of sequence-specific DNA bindiIEAbiological_process
GO:0032813tumor necrosis factor receptor superfamily bindingIEAmolecular_function
GO:0032755positive regulation of interleukin-6 productionIDAbiological_process
GO:0008203cholesterol metabolic processIEAbiological_process
GO:0002726positive regulation of T cell cytokine productionIEAbiological_process
GO:0032729positive regulation of interferon-gamma productionIEAbiological_process
GO:0050871positive regulation of B cell activationIEAbiological_process
GO:0032743positive regulation of interleukin-2 productionIEAbiological_process
GO:0032753positive regulation of interleukin-4 productionIDAbiological_process
GO:0071380cellular response to prostaglandin E stimulusIDAbiological_process
GO:0046641positive regulation of alpha-beta T cell proliferaIEAbiological_process
GO:0001816cytokine productionIEAbiological_process
GO:0051024positive regulation of immunoglobulin secretionISSbiological_process
GO:0016020membraneIEAcellular_component
GO:0042221response to chemical stimulusISSbiological_process
GO:0002819regulation of adaptive immune responseISSbiological_process
GO:0032733positive regulation of interleukin-10 productionIEAbiological_process
GO:0002526acute inflammatory responseIEAbiological_process
GO:0009615response to virusIEAbiological_process
GO:0032689negative regulation of interferon-gamma productionISSbiological_process
GO:0050871positive regulation of B cell activationISSbiological_process
GO:0009986cell surfaceIEAcellular_component
GO:0009615response to virusISSbiological_process
GO:0032729positive regulation of interferon-gamma productionIDAbiological_process
GO:0045590negative regulation of regulatory T cell differentISSbiological_process
GO:0032689negative regulation of interferon-gamma productionIEAbiological_process
GO:0002830positive regulation of type 2 immune responseIEAbiological_process
GO:0005615extracellular spaceIDAcellular_component
GO:0046641positive regulation of alpha-beta T cell proliferaISSbiological_process
GO:0005125cytokine activityIEAmolecular_function
GO:0071954chemokine (C-C motif) ligand 11 productionISSbiological_process
GO:0043433negative regulation of sequence-specific DNA bindiISSbiological_process
GO:0032755positive regulation of interleukin-6 productionIEAbiological_process
GO:0002891positive regulation of immunoglobulin mediated immIEAbiological_process
GO:0035708interleukin-4-dependent isotype switching to IgE iISSbiological_process
GO:0007165signal transductionTASbiological_process
GO:0045892negative regulation of transcription, DNA-dependenISSbiological_process
GO:0005887integral to plasma membraneNAScellular_component
GO:0045626negative regulation of T-helper 1 cell differentiaIEAbiological_process
GO:0032813tumor necrosis factor receptor superfamily bindingISSmolecular_function
GO:0045630positive regulation of T-helper 2 cell differentiaISSbiological_process
GO:0043382positive regulation of memory T cell differentiatiIEAbiological_process
GO:0035709memory T cell activationIEAbiological_process
GO:0043372positive regulation of CD4-positive, alpha-beta T IEAbiological_process
GO:0042104positive regulation of activated T cell proliferatIEAbiological_process
GO:0071222cellular response to lipopolysaccharideIDAbiological_process
GO:0006954inflammatory responseIEAbiological_process
GO:2000525positive regulation of T cell costimulationIEAbiological_process
GO:0032735positive regulation of interleukin-12 productionIEAbiological_process
GO:0045630positive regulation of T-helper 2 cell differentiaIEAbiological_process
GO:0002726positive regulation of T cell cytokine productionISSbiological_process
GO:0045626negative regulation of T-helper 1 cell differentiaISSbiological_process
GO:0005515protein bindingIEAmolecular_function
GO:0035712T-helper 2 cell activationISSbiological_process
GO:0008284positive regulation of cell proliferationTASbiological_process
GO:0002215defense response to nematodeIEAbiological_process
GO:0002830positive regulation of type 2 immune responseISSbiological_process
GO:0032753positive regulation of interleukin-4 productionIEAbiological_process
GO:0043372positive regulation of CD4-positive, alpha-beta T ISSbiological_process
GO:0050727regulation of inflammatory responseIEAbiological_process
GO:0009986cell surfaceIDAcellular_component
GO:0002215defense response to nematodeISSbiological_process
GO:0050710negative regulation of cytokine secretionIEAbiological_process
GO:0042221response to chemical stimulusIEAbiological_process
GO:0002526acute inflammatory responseISSbiological_process
GO:1900281positive regulation of CD4-positive, alpha beta T ISSbiological_process
GO:0050729positive regulation of inflammatory responseIDAbiological_process