| UniProt/SwissProt ID: | TNF13_HUMAN |
| Description: | tumor necrosis factor (ligand) superfamily, member 13 [Source:HGNC Symbol;Acc:11928] |
| Location: | chr17 p13.1 |
| Node attribute: | ligand; PPI(source) |
| Phosphorylation site |
| Position | PhosphoPeptide | Catalytic kinase | Source |
|---|---|---|---|
| Y153 | LQAQGyGVRIQ | TNF | PhosphoSitePlus |
| S213 | YNSCYsAGVFH | TNF | PhosphoSitePlus |
| S226 | QGDILsVIIPR | TNF | PhosphoSitePlus |
| T108 | RRAVLtQKQKK | PhosphoSitePlus | |
| Y212 | AYNSCySAGVF | TNF | PhosphoSitePlus |
| Dephosphorylation site |
| TNF13_HUMAN do not have dephosphorylation site. |
| Mutation site |
| Ensembl ID | Variation | Source | Cancer name | Pubmed |
|---|---|---|---|---|
| ENSP00000379794 | *248K | COSMIC | Head and Neck Cancer | 21798893 |
| Differential expressed protein |
| TNF13_HUMAN is not differential expressed protein. |
| Hyperphosphorylation site |
| TNF13_HUMAN do not have hyperphosphorylation site. |
| Direct Interaction Pair |
| Source | Target | Relationship | Resource |
|---|---|---|---|
| TNF13_HUMAN | TNR17_HUMAN | ligand -> receptor | HPMR |
| TNF13_HUMAN | TR13B_HUMAN | ligand -> receptor | HPMR |
| TNF13_HUMAN | TNR17_HUMAN | other | KEGG |
| TNF13_HUMAN | TR13B_HUMAN | other | KEGG |
| Function Annotation |
| KEGG Pathway |
| KEGG ID | Pathway |
|---|---|
| hsa04672 | Intestinal immune network for IgA production |
| hsa05323 | Rheumatoid arthritis |
| hsa04060 | Cytokine-cytokine receptor interaction |
| Gene Ontology |
| GO ID | GO_Term | Evidence | Ontology |
|---|---|---|---|
| GO:0009897 | external side of plasma membrane | IEA | cellular_component |
| GO:0048298 | positive regulation of isotype switching to IgA is | IDA | biological_process |
| GO:0008284 | positive regulation of cell proliferation | IEA | biological_process |
| GO:0007165 | signal transduction | TAS | biological_process |
| GO:0005829 | cytosol | TAS | cellular_component |
| GO:0005515 | protein binding | IEA | molecular_function |
| GO:0006955 | immune response | IEA | biological_process |
| GO:0005615 | extracellular space | IEA | cellular_component |
| GO:0002426 | immunoglobulin production in mucosal tissue | IEA | biological_process |
| GO:0016071 | mRNA metabolic process | TAS | biological_process |
| GO:0016020 | membrane | IEA | cellular_component |
| GO:0048298 | positive regulation of isotype switching to IgA is | IEA | biological_process |
| GO:0005654 | nucleoplasm | TAS | cellular_component |
| GO:0005102 | receptor binding | TAS | molecular_function |
| GO:0010467 | gene expression | TAS | biological_process |
| GO:0016070 | RNA metabolic process | TAS | biological_process |
| GO:0002636 | positive regulation of germinal center formation | IEA | biological_process |
| GO:0005164 | tumor necrosis factor receptor binding | IEA | molecular_function |
| GO:0005125 | cytokine activity | IEA | molecular_function |