Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:TIMP1_HUMAN
Description:TIMP metallopeptidase inhibitor 1 [Source:HGNC Symbol;Acc:11820]
Location:chrX p11.23
Node attribute:gene

Phosphorylation site
TIMP1_HUMAN do not have phosphorylation site.

Dephosphorylation site
TIMP1_HUMAN do not have dephosphorylation site.

Mutation site
TIMP1_HUMAN do not have mutation site.

Differential expressed protein
Ensembl IDCancer nameDesignSampleChangeRatioPubmed
ENSP00000218388Lung CancerCancer vs. Cancercell lineUp17284061
ENSP00000218388Breast CancerNormal vs. Cancercell lineDown0.2719053080

Hyperphosphorylation site
TIMP1_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
ETS1_HUMANTIMP1_HUMANTF -> target geneTRANSFAC

Function Annotation
KEGG Pathway
TIMP1_HUMAN is not in KEGG pathway.

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0007596blood coagulationTASbiological_process
GO:0001775cell activationIEAbiological_process
GO:0034097response to cytokine stimulusIEAbiological_process
GO:0005604basement membraneIEAcellular_component
GO:0005515protein bindingIPImolecular_function
GO:0046872metal ion bindingIEAmolecular_function
GO:0005576extracellular regionNAScellular_component
GO:0008191metalloendopeptidase inhibitor activityIEAmolecular_function
GO:0043066negative regulation of apoptotic processIEAbiological_process
GO:0031012extracellular matrixIEAcellular_component
GO:0010033response to organic substanceIEAbiological_process
GO:0002576platelet degranulationTASbiological_process
GO:0008284positive regulation of cell proliferationTASbiological_process
GO:1901164negative regulation of trophoblast cell migrationIMPbiological_process
GO:0043434response to peptide hormone stimulusIEAbiological_process
GO:0022617extracellular matrix disassemblyTASbiological_process
GO:0042060wound healingIEAbiological_process
GO:0043249erythrocyte maturationIEAbiological_process
GO:0031093platelet alpha granule lumenTAScellular_component
GO:0007568agingIEAbiological_process
GO:0030198extracellular matrix organizationTASbiological_process
GO:0005578proteinaceous extracellular matrixIEAcellular_component
GO:0030168platelet activationTASbiological_process
GO:0051045negative regulation of membrane protein ectodomainIDAbiological_process


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