Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:TGBR3_HUMAN
Description:transforming growth factor, beta receptor III [Source:HGNC Symbol;Acc:11774]
Location:chr1 p22.1
Node attribute:receptor

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
T843GSTQStPCSSSPhosphoSitePlus
S831PASENsSAAHSPhosphoSitePlus

Dephosphorylation site
TGBR3_HUMAN do not have dephosphorylation site.

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000212355Y212CCOSMICSkin Cancer21984974
ENSP00000212355S767TCOSMICOvarian Cancer21720365
ENSP00000212355H94NCOSMICOvarian Cancer21720365

Differential expressed protein
TGBR3_HUMAN is not differential expressed protein.

Hyperphosphorylation site
TGBR3_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
INHA_HUMANTGBR3_HUMANligand -> receptorHPMR

Function Annotation
KEGG Pathway
TGBR3_HUMAN is not in KEGG pathway.

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0005515protein bindingIEAmolecular_function
GO:0050680negative regulation of epithelial cell proliferatiIEAbiological_process
GO:0010633negative regulation of epithelial cell migrationIEAbiological_process
GO:0007243intracellular protein kinase cascadeIMPbiological_process
GO:0032354response to follicle-stimulating hormone stimulusIDAbiological_process
GO:0017134fibroblast growth factor bindingIEAmolecular_function
GO:0051092positive regulation of NF-kappaB transcription facIEAbiological_process
GO:0016049cell growthIEAbiological_process
GO:0009897external side of plasma membraneIDAcellular_component
GO:0055010ventricular cardiac muscle tissue morphogenesisIEAbiological_process
GO:0007179transforming growth factor beta receptor signalingIEAbiological_process
GO:0043393regulation of protein bindingIEAbiological_process
GO:0016477cell migrationISSbiological_process
GO:0001701in utero embryonic developmentIEAbiological_process
GO:0060317cardiac epithelial to mesenchymal transitionIDAbiological_process
GO:0060318definitive erythrocyte differentiationIEAbiological_process
GO:0005515protein bindingIPImolecular_function
GO:0005114type II transforming growth factor beta receptor bIDAmolecular_function
GO:0050431transforming growth factor beta bindingIEAmolecular_function
GO:0034673inhibin-betaglycan-ActRII complexIDAcellular_component
GO:0010719negative regulation of epithelial to mesenchymal tIEAbiological_process
GO:0009986cell surfaceIEAcellular_component
GO:0060347heart trabecula formationIEAbiological_process
GO:0005783endoplasmic reticulumIEAcellular_component
GO:0006461protein complex assemblyIEAbiological_process
GO:0060389pathway-restricted SMAD protein phosphorylationIEAbiological_process
GO:0030509BMP signaling pathwayIDAbiological_process
GO:0060216definitive hemopoiesisISSbiological_process
GO:0006955immune responseIMPbiological_process
GO:0051271negative regulation of cellular component movementIDAbiological_process
GO:0060021palate developmentIEAbiological_process
GO:0005615extracellular spaceIEAcellular_component
GO:0001889liver developmentIEAbiological_process
GO:0001666response to hypoxiaIEAbiological_process
GO:0015026coreceptor activityIDAmolecular_function
GO:0005024transforming growth factor beta-activated receptorIDAmolecular_function
GO:0030512negative regulation of transforming growth factor IEAbiological_process
GO:0034699response to luteinizing hormone stimulusIDAbiological_process
GO:0030511positive regulation of transforming growth factor IEAbiological_process
GO:0005024transforming growth factor beta-activated receptorIEAmolecular_function
GO:0034695response to prostaglandin E stimulusIDAbiological_process
GO:0060038cardiac muscle cell proliferationIEAbiological_process
GO:0008201heparin bindingIEAmolecular_function
GO:0030165PDZ domain bindingIEAmolecular_function
GO:0007179transforming growth factor beta receptor signalingIMPbiological_process
GO:0060216definitive hemopoiesisIEAbiological_process
GO:0005539glycosaminoglycan bindingISSmolecular_function
GO:0001837epithelial to mesenchymal transitionIDAbiological_process
GO:0003007heart morphogenesisISSbiological_process
GO:0046332SMAD bindingIEAmolecular_function
GO:0001824blastocyst developmentIEAbiological_process
GO:0005887integral to plasma membraneIEAcellular_component
GO:0070123transforming growth factor beta receptor activity,IEAmolecular_function
GO:0048185activin bindingIEAmolecular_function
GO:0005578proteinaceous extracellular matrixIEAcellular_component
GO:0005160transforming growth factor beta receptor bindingIEAmolecular_function
GO:0005539glycosaminoglycan bindingIEAmolecular_function
GO:0031100organ regenerationIEAbiological_process
GO:0005737cytoplasmIEAcellular_component
GO:0001568blood vessel developmentIEAbiological_process
GO:0007181transforming growth factor beta receptor complex aIEAbiological_process