Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:TFF1_HUMAN
Description:trefoil factor 1 [Source:HGNC Symbol;Acc:11755]
Location:chr21 q22.3
Node attribute:gene

Phosphorylation site
TFF1_HUMAN do not have phosphorylation site.

Dephosphorylation site
TFF1_HUMAN do not have dephosphorylation site.

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000291527A34DHPIGastric Cancer10982763 16697734
ENSP00000291527E37KHPIGastric Cancer10982763 16697734
ENSP00000291527G55VHPIGastric Cancer10982763
ENSP00000291527T32KHPIGastric Cancer10982763

Differential expressed protein
Ensembl IDCancer nameDesignSampleChangeRatioPubmed
ENSP00000291527Breast CancerTreatment (none vs. 17b-Estradiol treatment)cell lineUp8.418491314
ENSP00000291527Breast CancerNormal vs. CancertissueUp20560667

Hyperphosphorylation site
TFF1_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
ESR2_HUMANTFF1_HUMANTF -> target geneTRANSFAC
AHR_HUMANTFF1_HUMANTF -> target geneTRANSFAC

Function Annotation
KEGG Pathway
TFF1_HUMAN is not in KEGG pathway.

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0043434response to peptide hormone stimulusIEAbiological_process
GO:0008083growth factor activityIEAmolecular_function
GO:0006950response to stressIEAbiological_process
GO:0007586digestionNASbiological_process
GO:0030277maintenance of gastrointestinal epitheliumIEAbiological_process
GO:0005615extracellular spaceIEAcellular_component
GO:0005975carbohydrate metabolic processTASbiological_process
GO:0010039response to iron ionIEAbiological_process
GO:0005515protein bindingIPImolecular_function
GO:0032355response to estradiol stimulusIDAbiological_process