Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:TF2H1_HUMAN
Description:general transcription factor IIH, polypeptide 1, 62kDa [Source:HGNC Symbol;Acc:4655]
Location:chr11 p15.1
Node attribute:kinase

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
T42GKDRFtISHMYPhosphoSitePlus
S239RLNTGsKDLFAPhosphoSitePlus
S339NMDGNsGDADCHPRD
Y47TISHMyADIKCPhosphoSitePlus
Y360QESIEyEDLGKPhosphoSitePlus
S368LGKNNsVKTIAPhosphoSitePlus; HPRD

Dephosphorylation site
TF2H1_HUMAN do not have dephosphorylation site.

Mutation site
TF2H1_HUMAN do not have mutation site.

Differential expressed protein
TF2H1_HUMAN is not differential expressed protein.

Hyperphosphorylation site
TF2H1_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
TF2H1_HUMANE2F1_HUMANkinase -> substrateHPRD

Function Annotation
KEGG Pathway
KEGG IDPathway
hsa03420Nucleotide excision repair
hsa05203Viral carcinogenesis
hsa03022Basal transcription factors

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0006360transcription from RNA polymerase I promoterTASbiological_process
GO:0006362transcription elongation from RNA polymerase I proTASbiological_process
GO:0005515protein bindingIPImolecular_function
GO:0050434positive regulation of viral transcriptionTASbiological_process
GO:0010467gene expressionTASbiological_process
GO:0006367transcription initiation from RNA polymerase II prTASbiological_process
GO:0006289nucleotide-excision repairTASbiological_process
GO:0006283transcription-coupled nucleotide-excision repairTASbiological_process
GO:0004672protein kinase activityIDAmolecular_function
GO:0006363termination of RNA polymerase I transcriptionTASbiological_process
GO:00063707-methylguanosine mRNA cappingTASbiological_process
GO:0006468protein phosphorylationIDAbiological_process
GO:0006368transcription elongation from RNA polymerase II prTASbiological_process
GO:0006366transcription from RNA polymerase II promoterIDAbiological_process
GO:0000718nucleotide-excision repair, DNA damage removalTASbiological_process
GO:0008353RNA polymerase II carboxy-terminal domain kinase aIDAmolecular_function
GO:0000079regulation of cyclin-dependent protein kinase actiTASbiological_process
GO:0016032viral reproductionTASbiological_process
GO:0006361transcription initiation from RNA polymerase I proTASbiological_process
GO:0008094DNA-dependent ATPase activityIDAmolecular_function
GO:0006281DNA repairTASbiological_process
GO:0005654nucleoplasmTAScellular_component
GO:0045944positive regulation of transcription from RNA polyIDAbiological_process
GO:0005675holo TFIIH complexIDAcellular_component
GO:0005634nucleusIEAcellular_component


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