| UniProt/SwissProt ID: | TCAL6_HUMAN |
| Description: | transcription elongation factor A (SII)-like 6 [Source:HGNC Symbol;Acc:24553] |
| Location: | chrX q22.1 |
| Node attribute: | substrate |
| Phosphorylation site |
| Position | PhosphoPeptide | Catalytic kinase | Source |
|---|---|---|---|
| S135 | QERHLsSEEMM | BEX | PhosphoSitePlus |
| T118 | KTDRGtDDSPK | BEX | PhosphoSitePlus |
| S125 | DSPKDsQEDLQ | BEX | PhosphoSitePlus |
| S121 | RGTDDsPKDSQ | BEX | PhosphoSitePlus |
| S125 | DSPKDsQEDLQ | HPRD; phosphoELM | |
| Dephosphorylation site |
| TCAL6_HUMAN do not have dephosphorylation site. |
| Mutation site |
| Ensembl ID | Variation | Source | Cancer name | Pubmed |
|---|---|---|---|---|
| ENSP00000361859 | E98K | COSMIC | Head and Neck Cancer | 21798893 | ENSP00000361859 | A38T | COSMIC | Ovarian Cancer | 21720365 | ENSP00000361859 | R116W | COSMIC | Head and Neck Cancer | 21798893 |
| Differential expressed protein |
| TCAL6_HUMAN is not differential expressed protein. |
| Hyperphosphorylation site |
| TCAL6_HUMAN do not have hyperphosphorylation site. |
| Direct Interaction Pair |
| Source | Target | Relationship | Resource |
|---|---|---|---|
| KPCA_HUMAN | TCAL6_HUMAN | kinase -> substrate | Robert H Newman (2013) |
| AKT1_HUMAN | TCAL6_HUMAN | kinase -> substrate | Robert H Newman (2013) |
| Function Annotation |
| KEGG Pathway |
| TCAL6_HUMAN is not in KEGG pathway. |
| Gene Ontology |
| GO ID | GO_Term | Evidence | Ontology |
|---|---|---|---|
| GO:0006351 | transcription, DNA-dependent | IEA | biological_process |
| GO:0005634 | nucleus | IEA | cellular_component |
| GO:0006355 | regulation of transcription, DNA-dependent | IEA | biological_process |