Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:SPF30_HUMAN
Description:survival motor neuron domain containing 1 [Source:HGNC Symbol;Acc:16900]
Location:chr10 q25.2
Node attribute:substrate

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
Y224KPMTQyQDTSKPhosphoSitePlus
T206SPESVtGKVGVDUF3703PhosphoSitePlus
T57TQPSEtLASSDPhosphoSitePlus
S66SDSFAsTQPTHSMNPhosphoSitePlus
T222ADKPMtQYQDTDUF3703PhosphoSitePlus
T213KVGVGtCGIADDUF3703PhosphoSitePlus
T227TQYQDtSKYNVPhosphoSitePlus
S201RSIFAsPESVTDUF3703PhosphoSitePlus; SysPTM
S201RSIFAsPESVTHPRD; phosphoELM; SysPTM
S51TKDLLsTQPSEPhosphoSitePlus
T52KDLLStQPSETPhosphoSitePlus
T67DSFAStQPTHSSMNPhosphoSitePlus
S204FASPEsVTGKVDUF3703PhosphoSitePlus

Dephosphorylation site
SPF30_HUMAN do not have dephosphorylation site.

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000358605N189KCOSMICMelanoma21499247

Differential expressed protein
SPF30_HUMAN is not differential expressed protein.

Hyperphosphorylation site
SPF30_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
CLK2_HUMANSPF30_HUMANkinase -> substrateRobert H Newman (2013)

Function Annotation
KEGG Pathway
SPF30_HUMAN is not in KEGG pathway.

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0015030Cajal bodyIEAcellular_component
GO:0000375RNA splicing, via transesterification reactionsTASbiological_process
GO:0005737cytoplasmIEAcellular_component
GO:0005515protein bindingIPImolecular_function
GO:0006917induction of apoptosisTASbiological_process
GO:0006397mRNA processingIEAbiological_process
GO:0008380RNA splicingTASbiological_process
GO:0005634nucleusTAScellular_component
GO:0005681spliceosomal complexIEAcellular_component
GO:0003723RNA bindingIEAmolecular_function
GO:0016607nuclear speckIEAcellular_component
GO:0006915apoptotic processIEAbiological_process


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