| UniProt/SwissProt ID: | SHBG_HUMAN |
| Description: | sex hormone-binding globulin [Source:HGNC Symbol;Acc:10839] |
| Location: | chr17 p13.1 |
| Node attribute: | gene |
| Phosphorylation site |
| Position | PhosphoPeptide | Catalytic kinase | Source |
|---|---|---|---|
| Y86 | EGVIFyGDTNP | HPRD; SysPTM | |
| T161 | VSGPLtSKRHP | Laminin_G_1 | PhosphoSitePlus |
| Dephosphorylation site |
| SHBG_HUMAN do not have dephosphorylation site. |
| Mutation site |
| Ensembl ID | Variation | Source | Cancer name | Pubmed |
|---|---|---|---|---|
| ENSP00000369816 | P223L | COSMIC | Skin Cancer | 21984974 |
| Differential expressed protein |
| SHBG_HUMAN is not differential expressed protein. |
| Hyperphosphorylation site |
| SHBG_HUMAN do not have hyperphosphorylation site. |
| Direct Interaction Pair |
| Source | Target | Relationship | Resource |
|---|---|---|---|
| HNF4A_HUMAN | SHBG_HUMAN | TF -> target gene | TRANSFAC |
| Function Annotation |
| KEGG Pathway |
| SHBG_HUMAN is not in KEGG pathway. |
| Gene Ontology |
| GO ID | GO_Term | Evidence | Ontology |
|---|---|---|---|
| GO:0005576 | extracellular region | NAS | cellular_component |
| GO:0042803 | protein homodimerization activity | NAS | molecular_function |
| GO:0005515 | protein binding | IEA | molecular_function |
| GO:0009914 | hormone transport | NAS | biological_process |
| GO:0007285 | primary spermatocyte growth | IEA | biological_process |
| GO:0005497 | androgen binding | TAS | molecular_function |