Phosphorylation

Protein information

UniProt/SwissProt ID:	RUXE_HUMAN
Description:	small nuclear ribonucleoprotein polypeptide E [Source:HGNC Symbol;Acc:11161]
Location:	chr1 q32.1
Node attribute:	substrate

Position	PhosphoPeptide	Catalytic kinase	Source
T68	EIHSKtKSRKQ	LSM	PhosphoSitePlus

RUXE_HUMAN do not have dephosphorylation site.

Ensembl ID	Variation	Source	Cancer name	Pubmed
ENSP00000400591	D51V	BIOMART	Breast Cancer	21930507, 21930502

Ensembl ID	Cancer name	Design	Sample	Change	Ratio	Pubmed
ENSP00000400591	hepatitis B virus	Normal vs. Cancer	tissue	Up	100	14726492

RUXE_HUMAN do not have hyperphosphorylation site.

Source	Target	Relationship	Resource
ARAF_HUMAN	RUXE_HUMAN	kinase -> substrate	Robert H Newman (2013)

KEGG Pathway

RUXE_HUMAN is not in KEGG pathway.

Gene Ontology

GO ID	GO_Term	Evidence	Ontology
GO:0016070	RNA metabolic process	TAS	biological_process
GO:0006397	mRNA processing	TAS	biological_process
GO:0008380	RNA splicing	TAS	biological_process
GO:0010467	gene expression	TAS	biological_process
GO:0000398	mRNA splicing, via spliceosome	IC	biological_process
GO:0071013	catalytic step 2 spliceosome	IDA	cellular_component
GO:0005681	spliceosomal complex	NAS	cellular_component
GO:0030532	small nuclear ribonucleoprotein complex	NAS	cellular_component
GO:0003723	RNA binding	IEA	molecular_function
GO:0000387	spliceosomal snRNP assembly	TAS	biological_process
GO:0008334	histone mRNA metabolic process	TAS	biological_process
GO:0005515	protein binding	IPI	molecular_function
GO:0005683	U7 snRNP	IDA	cellular_component
GO:0005689	U12-type spliceosomal complex	IDA	cellular_component
GO:0006366	transcription from RNA polymerase II promoter	TAS	biological_process
GO:0005654	nucleoplasm	TAS	cellular_component
GO:0005829	cytosol	TAS	cellular_component
GO:0006369	termination of RNA polymerase II transcription	TAS	biological_process
GO:0034660	ncRNA metabolic process	TAS	biological_process
GO:0000245	spliceosomal complex assembly	NAS	biological_process

Human Phosphorylation Mediated
Signaling Transduction Network