| UniProt/SwissProt ID: | RRAGC_HUMAN |
| Description: | Ras-related GTP binding C [Source:HGNC Symbol;Acc:19902] |
| Location: | chr1 p34.3 |
| Node attribute: | substrate |
| Phosphorylation site |
| Position | PhosphoPeptide | Catalytic kinase | Source |
|---|---|---|---|
| Y16 | PLAGSyGAADS | HPRD | |
| S95 | TLFLEsTNKIY | Gtr1_RagA | PhosphoSitePlus; SysPTM |
| T394 | LTHNGtPRNAI | PhosphoSitePlus | |
| S86 | VFHKMsPNETL | HPRD | |
| S2 | QYGA | HPRD | |
| S95 | TLFLEsTNKIY | HPRD; SysPTM | |
| S385 | QTSASsLKALT | PhosphoSitePlus | |
| Y327 | NTTVLyLKEVT | PhosphoSitePlus | |
| T381 | SCGHQtSASSL | PhosphoSitePlus | |
| S2 | ____MsLQYGA | PhosphoSitePlus | |
| T96 | LFLEStNKIYK | Gtr1_RagA | PhosphoSitePlus; SysPTM |
| S382 | CGHQTsASSLK | PhosphoSitePlus | |
| S21 | YGAADsFPKDF | PhosphoSitePlus; HPRD | |
| S384 | HQTSAsSLKAL | PhosphoSitePlus | |
| T96 | LFLEStNKIYK | HPRD; SysPTM | |
| S15 | TPLAGsYGAAD | PhosphoSitePlus; HPRD | |
| Dephosphorylation site |
| RRAGC_HUMAN do not have dephosphorylation site. |
| Mutation site |
| Ensembl ID | Variation | Source | Cancer name | Pubmed |
|---|---|---|---|---|
| ENSP00000362092 | Y165C | COSMIC | Ovarian Cancer | 21720365 |
| Differential expressed protein |
| RRAGC_HUMAN is not differential expressed protein. |
| Hyperphosphorylation site |
| RRAGC_HUMAN do not have hyperphosphorylation site. |
| Direct Interaction Pair |
| Source | Target | Relationship | Resource |
|---|---|---|---|
| PRP4B_HUMAN | RRAGC_HUMAN | kinase -> substrate | Robert H Newman (2013) |
| Function Annotation |
| KEGG Pathway |
| RRAGC_HUMAN is not in KEGG pathway. |
| Gene Ontology |
| GO ID | GO_Term | Evidence | Ontology |
|---|---|---|---|
| GO:0007264 | small GTPase mediated signal transduction | TAS | biological_process |
| GO:0034613 | cellular protein localization | ISS | biological_process |
| GO:0006915 | apoptotic process | NAS | biological_process |
| GO:0008380 | RNA splicing | NAS | biological_process |
| GO:0032008 | positive regulation of TOR signaling cascade | NAS | biological_process |
| GO:0016049 | cell growth | NAS | biological_process |
| GO:0005515 | protein binding | IPI | molecular_function |
| GO:0006351 | transcription, DNA-dependent | NAS | biological_process |
| GO:0005764 | lysosome | IDA | cellular_component |
| GO:0003924 | GTPase activity | IDA | molecular_function |
| GO:0071230 | cellular response to amino acid stimulus | ISS | biological_process |
| GO:0005737 | cytoplasm | IDA | cellular_component |
| GO:0019003 | GDP binding | IDA | molecular_function |
| GO:0005634 | nucleus | IDA | cellular_component |
| GO:0000287 | magnesium ion binding | NAS | molecular_function |
| GO:0046982 | protein heterodimerization activity | IPI | molecular_function |
| GO:0005525 | GTP binding | IDA | molecular_function |
| GO:0006184 | GTP catabolic process | IDA | biological_process |