Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:ROBO4_HUMAN
Description:roundabout, axon guidance receptor, homolog 4 (Drosophila) [Source:HGNC Symbol;Acc:17985]
Location:chr11 q24.2
Node attribute:receptor

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
S3___MGsGGDSLPhosphoSitePlus
S656LQHANsSPLLRPhosphoSitePlus
S542DLSSSsSLSSRHPRD
S539GSRDLsSSSSLHPRD
S131RGARLsVAVLRI-setPhosphoSitePlus

Dephosphorylation site
ROBO4_HUMAN do not have dephosphorylation site.

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000304945G328DCOSMICSkin Cancer21984974
ENSP00000304945A495DCOSMICOvarian Cancer21720365
ENSP00000304945L703FCOSMICSkin Cancer21984974
ENSP00000304945W162*COSMICSkin Cancer21984974
ENSP00000304945G662ABIOMARTBreast Cancer21930507, 21930502

Differential expressed protein
ROBO4_HUMAN is not differential expressed protein.

Hyperphosphorylation site
ROBO4_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
SLIT2_HUMANROBO4_HUMANligand -> receptorHPMR

Function Annotation
KEGG Pathway
ROBO4_HUMAN is not in KEGG pathway.

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0030334regulation of cell migrationNASbiological_process
GO:0001525angiogenesisIGIbiological_process
GO:0016021integral to membraneTAScellular_component
GO:0009897external side of plasma membraneIEAcellular_component
GO:0030154cell differentiationIEAbiological_process
GO:0004872receptor activityIEAmolecular_function
GO:0030336negative regulation of cell migrationIEAbiological_process
GO:0005515protein bindingIEAmolecular_function


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