| UniProt/SwissProt ID: | RFRP_HUMAN |
| Description: | neuropeptide VF precursor [Source:HGNC Symbol;Acc:13782] |
| Location: | chr7 p15.3 |
| Node attribute: | ligand |
| Phosphorylation site |
| Position | PhosphoPeptide | Catalytic kinase | Source |
|---|---|---|---|
| T75 | VIKMStPAVNK | PhosphoSitePlus | |
| T135 | RFGRTtTAKSV | PhosphoSitePlus | |
| T136 | FGRTTtAKSVC | PhosphoSitePlus | |
| T134 | QRFGRtTTAKS | PhosphoSitePlus | |
| Dephosphorylation site |
| RFRP_HUMAN do not have dephosphorylation site. |
| Mutation site |
| Ensembl ID | Variation | Source | Cancer name | Pubmed |
|---|---|---|---|---|
| ENSP00000222674 | T16S | COSMIC | Ovarian Cancer | 21720365 |
| Differential expressed protein |
| RFRP_HUMAN is not differential expressed protein. |
| Hyperphosphorylation site |
| RFRP_HUMAN do not have hyperphosphorylation site. |
| Direct Interaction Pair |
| Source | Target | Relationship | Resource |
|---|---|---|---|
| RFRP_HUMAN | NPFF1_HUMAN | ligand -> receptor | HPMR |
| Function Annotation |
| KEGG Pathway |
| RFRP_HUMAN is not in KEGG pathway. |
| Gene Ontology |
| GO ID | GO_Term | Evidence | Ontology |
|---|---|---|---|
| GO:0016020 | membrane | NAS | cellular_component |
| GO:0032277 | negative regulation of gonadotropin secretion | IDA | biological_process |
| GO:0004930 | G-protein coupled receptor activity | NAS | molecular_function |
| GO:0005576 | extracellular region | IEA | cellular_component |
| GO:0007218 | neuropeptide signaling pathway | NAS | biological_process |