Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:RENI_HUMAN
Description:renin [Source:HGNC Symbol;Acc:9958]
Location:chr1 q32.1
Node attribute:ligand

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
S45PSIREsLKERGA1_PropeptidePhosphoSitePlus
T330CNEGPtLPDISAspPhosphoSitePlus
Y87MDTQYyGEIGIAspPhosphoSitePlus
S347EYTLTsADYVFAspPhosphoSitePlus
S41LKRMPsIRESLA1_PropeptidePhosphoSitePlus
S355YVFQEsYSSKKAspPhosphoSitePlus

Dephosphorylation site
RENI_HUMAN do not have dephosphorylation site.

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000356163*404SCOSMICCentral Nervous System Neoplasms10560660

Differential expressed protein
RENI_HUMAN is not differential expressed protein.

Hyperphosphorylation site
RENI_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
RENI_HUMANRENR_HUMANligand -> receptorHPMR

Function Annotation
KEGG Pathway
KEGG IDPathway
hsa04614Renin-angiotensin system

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0005615extracellular spaceIDAcellular_component
GO:0002003angiotensin maturationIDAbiological_process
GO:0044444cytoplasmic partIEAcellular_component
GO:0043408regulation of MAPK cascadeIDAbiological_process
GO:0008233peptidase activityIDAmolecular_function
GO:0001823mesonephros developmentIEAbiological_process
GO:0016020membraneIEAcellular_component
GO:0008584male gonad developmentIEAbiological_process
GO:0005615extracellular spaceIEAcellular_component
GO:0005622intracellularIEAcellular_component
GO:0009755hormone-mediated signaling pathwayIEAbiological_process
GO:0042756drinking behaviorIEAbiological_process
GO:0035690cellular response to drugIEAbiological_process
GO:0032496response to lipopolysaccharideIEAbiological_process
GO:0051591response to cAMPIEAbiological_process
GO:0042493response to drugIEAbiological_process
GO:0070305response to cGMPIEAbiological_process
GO:0010033response to organic substanceIEAbiological_process
GO:0005159insulin-like growth factor receptor bindingIEAmolecular_function
GO:0050435beta-amyloid metabolic processIEAbiological_process
GO:0005102receptor bindingIEAmolecular_function
GO:0001822kidney developmentIMPbiological_process
GO:0004190aspartic-type endopeptidase activityIDAmolecular_function
GO:0004175endopeptidase activityIEAmolecular_function
GO:0006950response to stressIEAbiological_process
GO:0048469cell maturationIEAbiological_process
GO:0006508proteolysisIDAbiological_process
GO:0005102receptor bindingIPImolecular_function
GO:0008217regulation of blood pressureTASbiological_process
GO:0002003angiotensin maturationIEAbiological_process
GO:0002016regulation of blood volume by renin-angiotensinIEAbiological_process
GO:0002018renin-angiotensin regulation of aldosterone producIEAbiological_process


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