| UniProt/SwissProt ID: | PO2F3_HUMAN |
| Description: | POU class 2 homeobox 3 [Source:HGNC Symbol;Acc:19864] |
| Location: | chr11 q23.3 |
| Node attribute: | TF |
| Phosphorylation site |
| Position | PhosphoPeptide | Catalytic kinase | Source |
|---|---|---|---|
| S14 | TDIKMsGDVAD | PhosphoSitePlus | |
| S20 | GDVADsTDARS | PhosphoSitePlus | |
| S287 | RKKRTsIETNI | Homeobox | PhosphoSitePlus |
| T21 | DVADStDARST | PhosphoSitePlus | |
| S238 | EALNLsFKNMC | Pou | PhosphoSitePlus |
| S287 | RKKRTsIETNI | phosphoELM | |
| Dephosphorylation site |
| PO2F3_HUMAN do not have dephosphorylation site. |
| Mutation site |
| Ensembl ID | Variation | Source | Cancer name | Pubmed |
|---|---|---|---|---|
| ENSP00000260264 | R24C | COSMIC | Melanoma | 21499247 | ENSP00000260264 | R332* | TCGA, COSMIC | Ovarian Cancer | 21720365, 18772890 |
| Differential expressed protein |
| PO2F3_HUMAN is not differential expressed protein. |
| Hyperphosphorylation site |
| PO2F3_HUMAN do not have hyperphosphorylation site. |
| Direct Interaction Pair |
| Source | Target | Relationship | Resource |
|---|---|---|---|
| PO2F3_HUMAN | SPR2A_HUMAN | TF -> target gene | TRANSFAC |
| Function Annotation |
| KEGG Pathway |
| PO2F3_HUMAN is not in KEGG pathway. |
| Gene Ontology |
| GO ID | GO_Term | Evidence | Ontology |
|---|---|---|---|
| GO:0006355 | regulation of transcription, DNA-dependent | IEA | biological_process |
| GO:0003677 | DNA binding | IEA | molecular_function |
| GO:0030216 | keratinocyte differentiation | IEA | biological_process |
| GO:0042060 | wound healing | IEA | biological_process |
| GO:0003700 | sequence-specific DNA binding transcription factor | IEA | molecular_function |
| GO:0008544 | epidermis development | TAS | biological_process |
| GO:0043565 | sequence-specific DNA binding | IEA | molecular_function |
| GO:0008544 | epidermis development | IEA | biological_process |
| GO:0045944 | positive regulation of transcription from RNA poly | IEA | biological_process |
| GO:0005515 | protein binding | IPI | molecular_function |
| GO:0006351 | transcription, DNA-dependent | IEA | biological_process |
| GO:0006357 | regulation of transcription from RNA polymerase II | TAS | biological_process |
| GO:0005667 | transcription factor complex | IEA | cellular_component |
| GO:0043922 | negative regulation by host of viral transcription | IDA | biological_process |
| GO:0046983 | protein dimerization activity | IEA | molecular_function |
| GO:0005737 | cytoplasm | IDA | cellular_component |
| GO:0005634 | nucleus | IDA | cellular_component |