Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:PKR2_HUMAN
Description:prokineticin receptor 2 [Source:HGNC Symbol;Acc:15836]
Location:chr20 p12.3
Node attribute:receptor

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
T374TNGVPtTEEVDPhosphoSitePlus
T369DLDLRtNGVPTPhosphoSitePlus
S362RGSKSsADLDLPhosphoSitePlus

Dephosphorylation site
PKR2_HUMAN do not have dephosphorylation site.

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000217270R268GCOSMICHead and Neck Cancer21798893
ENSP00000217270D112YCOSMICHead and Neck Cancer21798893
ENSP00000217270V331MCOSMICPancreatic Cancer
ENSP00000217270R353HCOSMICOvarian Cancer21720365
ENSP00000217270M341IBIOMARTBreast Cancer21930507, 21930502
ENSP00000217270L95PCOSMICOvarian Cancer21720365
ENSP00000217270S138FCOSMICSkin Cancer21984974
ENSP00000217270S23FBIOMARTBreast Cancer21930507, 21930502
ENSP00000217270R85CCOSMICOvarian Cancer21720365
ENSP00000217270G293SBIOMARTBreast Cancer21930507, 21930502
ENSP00000217270M165ICOSMICCentral Nervous System Neoplasms18772396
ENSP00000217270C279SCOSMICHead and Neck Cancer21798893
ENSP00000217270R298CCOSMICOvarian Cancer21720365

Differential expressed protein
PKR2_HUMAN is not differential expressed protein.

Hyperphosphorylation site
PKR2_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
PROK2_HUMANPKR2_HUMANligand -> receptorHPMR
PROK1_HUMANPKR2_HUMANligand -> receptorHPMR

Function Annotation
KEGG Pathway
PKR2_HUMAN is not in KEGG pathway.

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0004983neuropeptide Y receptor activityIEAmolecular_function
GO:0004930G-protein coupled receptor activityIEAmolecular_function
GO:0007623circadian rhythmIEAbiological_process
GO:0007186G-protein coupled receptor signaling pathwayIEAbiological_process
GO:0016021integral to membraneIEAcellular_component
GO:0005886plasma membraneTAScellular_component


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