| UniProt/SwissProt ID: | PDYN_HUMAN |
| Description: | prodynorphin [Source:HGNC Symbol;Acc:8820] |
| Location: | chr20 p13 |
| Node attribute: | ligand |
| Phosphorylation site |
| Position | PhosphoPeptide | Catalytic kinase | Source |
|---|---|---|---|
| S101 | AKLSGsFLKEL | PhosphoSitePlus | |
| Dephosphorylation site |
| PDYN_HUMAN do not have dephosphorylation site. |
| Mutation site |
| Ensembl ID | Variation | Source | Cancer name | Pubmed |
|---|---|---|---|---|
| ENSP00000217305 | R180C | COSMIC | Ovarian Cancer | 21720365 | ENSP00000217305 | G193R | COSMIC | Skin Cancer | 21984974 | ENSP00000217305 | R232H | COSMIC | Head and Neck Cancer | 21798897 |
| Differential expressed protein |
| PDYN_HUMAN is not differential expressed protein. |
| Hyperphosphorylation site |
| PDYN_HUMAN do not have hyperphosphorylation site. |
| Direct Interaction Pair |
| Source | Target | Relationship | Resource |
|---|---|---|---|
| PDYN_HUMAN | OPRK_HUMAN | ligand -> receptor | HPMR |
| Function Annotation |
| KEGG Pathway |
| KEGG ID | Pathway |
|---|---|
| hsa05030 | Cocaine addiction |
| hsa05031 | Amphetamine addiction |
| hsa05034 | Alcoholism |
| Gene Ontology |
| GO ID | GO_Term | Evidence | Ontology |
|---|---|---|---|
| GO:0005576 | extracellular region | TAS | cellular_component |
| GO:0008219 | cell death | IEA | biological_process |
| GO:0005886 | plasma membrane | IDA | cellular_component |
| GO:0001515 | opioid peptide activity | IEA | molecular_function |
| GO:0007218 | neuropeptide signaling pathway | IEA | biological_process |
| GO:0007268 | synaptic transmission | IEA | biological_process |