Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:PDCD5_HUMAN
Description:programmed cell death 5 [Source:HGNC Symbol;Acc:8764]
Location:chr19 q13.11
Node attribute:substrate

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
Y80IQMARyGQLSEdsDNA_bind; Terminase_4PhosphoSitePlus
Y125DEDDDy_____PhosphoSitePlus
S119RKVMDsDEDDDTerminase_4PhosphoSitePlus
S119RKVMDsDEDDphosphoELM
Y73KAVENyLIQMAdsDNA_bind; Terminase_4PhosphoSitePlus

Dephosphorylation site
PDCD5_HUMAN do not have dephosphorylation site.

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000221784D122HBIOMARTBreast Cancer21930507, 21930502
ENSP00000221784R55SCOSMICLung Cancer
ENSP00000221784E85DCOSMICOvarian Cancer21720365

Differential expressed protein
Ensembl IDCancer nameDesignSampleChangeRatioPubmed
ENSP00000221784Non-small cell lung carcinomaMetastasiscell lineUp17537172
ENSP00000221784Renal CancerNormal vs. CancertissueDown0.3619610612

Hyperphosphorylation site
PDCD5_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
CDK4_HUMANPDCD5_HUMANkinase -> substrateRobert H Newman (2013)

Function Annotation
KEGG Pathway
PDCD5_HUMAN is not in KEGG pathway.

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0006915apoptotic processIEAbiological_process
GO:0003677DNA bindingIEAmolecular_function
GO:0005634nucleusIDAcellular_component
GO:0006917induction of apoptosisTASbiological_process
GO:0005737cytoplasmIDAcellular_component


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