| UniProt/SwissProt ID: | PACE1_HUMAN |
| Description: | SCY1-like 3 (S. cerevisiae) [Source:HGNC Symbol;Acc:19285] |
| Location: | chr1 q24.2 |
| Node attribute: | kinase |
| Phosphorylation site |
| Position | PhosphoPeptide | Catalytic kinase | Source |
|---|---|---|---|
| S391 | RDTSDsIVAIT | PhosphoSitePlus | |
| T153 | KVSQAtPEFLR | Pkinase | PhosphoSitePlus |
| S533 | EWPDWsEPEEP | PhosphoSitePlus | |
| S707 | KKDDVsPVMQF | PhosphoSitePlus | |
| S405 | LAVLVsLLGPE | PhosphoSitePlus | |
| S389 | GLRDTsDSIVA | PhosphoSitePlus | |
| Dephosphorylation site |
| PACE1_HUMAN do not have dephosphorylation site. |
| Mutation site |
| Ensembl ID | Variation | Source | Cancer name | Pubmed |
|---|---|---|---|---|
| ENSP00000356744 | E652Q | BIOMART | Breast Cancer | 21930507, 21930502 | ENSP00000356746 | E652Q | BIOMART | Breast Cancer | 21930507, 21930502 | ENSP00000356745 | E598Q | BIOMART | Breast Cancer | 21930507, 21930502 |
| Differential expressed protein |
| PACE1_HUMAN is not differential expressed protein. |
| Hyperphosphorylation site |
| PACE1_HUMAN do not have hyperphosphorylation site. |
| Direct Interaction Pair |
| Source | Target | Relationship | Resource |
|---|---|---|---|
| PACE1_HUMAN | CBL_HUMAN | kinase -> substrate | Robert H Newman (2013) |
| PACE1_HUMAN | TRI26_HUMAN | kinase -> substrate | Robert H Newman (2013) |
| Function Annotation |
| KEGG Pathway |
| PACE1_HUMAN is not in KEGG pathway. |
| Gene Ontology |
| GO ID | GO_Term | Evidence | Ontology |
|---|---|---|---|
| GO:0005794 | Golgi apparatus | IDA | cellular_component |
| GO:0030027 | lamellipodium | IDA | cellular_component |
| GO:0005488 | binding | IEA | molecular_function |
| GO:0005737 | cytoplasm | IDA | cellular_component |
| GO:0006468 | protein phosphorylation | IEA | biological_process |
| GO:0005524 | ATP binding | IEA | molecular_function |
| GO:0016477 | cell migration | NAS | biological_process |
| GO:0005515 | protein binding | IPI | molecular_function |
| GO:0016772 | transferase activity, transferring phosphorus-cont | IEA | molecular_function |
| GO:0004672 | protein kinase activity | IEA | molecular_function |