Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:OX1R_HUMAN
Description:hypocretin (orexin) receptor 1 [Source:HGNC Symbol;Acc:4848]
Location:chr1 p35.2
Node attribute:receptor; PPI(target)

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
Y358ANPIIyNFLSGTM; 7tm_1PhosphoSitePlus
Y124CKVIPyLQAVSTM; 7tm_1PhosphoSitePlus
Y83RTVTNyFIVNLTM; Form_Nir_trans; 7tm_1PhosphoSitePlus
Y27PVPPDyEDEFLPhosphoSitePlus; HPRD; phosphoELM
S138AVLTLsFIALDTM; 7tm_1PhosphoSitePlus

Dephosphorylation site
OX1R_HUMAN do not have dephosphorylation site.

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000384387V106LTCGAOvarian Cancer21720365, 18772890
ENSP00000362810V106LTCGA, COSMICOvarian Cancer21720365, 18772890

Differential expressed protein
OX1R_HUMAN is not differential expressed protein.

Hyperphosphorylation site
OX1R_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
OREX_HUMANOX1R_HUMANligand -> receptorHPMR
IP3KA_HUMANOX1R_HUMANotherKEGG

Function Annotation
KEGG Pathway
KEGG IDPathway
hsa04080Neuroactive ligand-receptor interaction

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0016499orexin receptor activityIEAmolecular_function
GO:0007218neuropeptide signaling pathwayIEAbiological_process
GO:0007268synaptic transmissionTASbiological_process
GO:0007631feeding behaviorTASbiological_process
GO:0005887integral to plasma membraneTAScellular_component
GO:0016021integral to membraneIEAcellular_component
GO:0004930G-protein coupled receptor activityTASmolecular_function
GO:0005886plasma membraneTAScellular_component
GO:0007186G-protein coupled receptor signaling pathwayIEAbiological_process
GO:0017046peptide hormone bindingIEAmolecular_function


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