| UniProt/SwissProt ID: | OCTC_HUMAN |
| Description: | carnitine O-octanoyltransferase [Source:HGNC Symbol;Acc:2366] |
| Location: | chr7 q21.12 |
| Node attribute: | kinase |
| Phosphorylation site |
| Position | PhosphoPeptide | Catalytic kinase | Source |
|---|---|---|---|
| S533 | PLFSKsGGGGN | Carn_acyltransf | PhosphoSitePlus |
| Y387 | QAKAQyLREAS | Carn_acyltransf | PhosphoSitePlus |
| Dephosphorylation site |
| OCTC_HUMAN do not have dephosphorylation site. |
| Mutation site |
| Ensembl ID | Variation | Source | Cancer name | Pubmed |
|---|---|---|---|---|
| ENSP00000331981 | H207R | Ding2008 | Lung Cancer | 18948947 | ENSP00000331981 | H207R | COSMIC | Lung Cancer | 18948947 | ENSP00000331981 | E52* | BIOMART | Breast Cancer | 21930507, 21930502 | ENSP00000331981 | *613W | COSMIC | Ovarian Cancer | 21720365 | ENSP00000331981 | K375E | COSMIC | Ovarian Cancer | 21720365 | ENSP00000331981 | *613Y | COSMIC | Renal Cancer | 21248752 |
| Differential expressed protein |
| OCTC_HUMAN is not differential expressed protein. |
| Hyperphosphorylation site |
| OCTC_HUMAN do not have hyperphosphorylation site. |
| Direct Interaction Pair |
| Source | Target | Relationship | Resource |
|---|---|---|---|
| OCTC_HUMAN | M3K14_HUMAN | kinase -> substrate | RegPhos |
| Function Annotation |
| KEGG Pathway |
| KEGG ID | Pathway |
|---|---|
| hsa04146 | Peroxisome |
| Gene Ontology |
| GO ID | GO_Term | Evidence | Ontology |
|---|---|---|---|
| GO:0044255 | cellular lipid metabolic process | TAS | biological_process |
| GO:0005777 | peroxisome | NAS | cellular_component |
| GO:0044281 | small molecule metabolic process | TAS | biological_process |
| GO:0008458 | carnitine O-octanoyltransferase activity | IDA | molecular_function |
| GO:0006631 | fatty acid metabolic process | IMP | biological_process |
| GO:0005782 | peroxisomal matrix | TAS | cellular_component |
| GO:0006810 | transport | IEA | biological_process |
| GO:0016746 | transferase activity, transferring acyl groups | IEA | molecular_function |
| GO:0043231 | intracellular membrane-bounded organelle | IDA | cellular_component |
| GO:0005102 | receptor binding | IPI | molecular_function |
| GO:0006635 | fatty acid beta-oxidation | IDA | biological_process |
| GO:0033540 | fatty acid beta-oxidation using acyl-CoA oxidase | TAS | biological_process |
| GO:0051791 | medium-chain fatty acid metabolic process | IDA | biological_process |
| GO:0006091 | generation of precursor metabolites and energy | IDA | biological_process |