Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:NR5A2_HUMAN
Description:nuclear receptor subfamily 5, group A, member 2 [Source:HGNC Symbol;Acc:7984]
Location:chr1 q32.1
Node attribute:TF

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
S383LQNCWsELLILHormone_recepPhosphoSitePlus
S243SPFVTsPISMTPhosphoSitePlus
S510EIRAIsMQAEEHormone_recepPhosphoSitePlus
T113GFFKRtVQNNKzf-C4PhosphoSitePlus
S238TDYDRsPFVTSPhosphoSitePlus

Dephosphorylation site
NR5A2_HUMAN do not have dephosphorylation site.

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000236914D129EBIOMARTPancreatic Cancer21930507, 21930502
ENSP00000356331N426HCOSMICOvarian Cancer21720365
ENSP00000356331D175EBIOMARTPancreatic Cancer21930507, 21930502
ENSP00000236914N380HTCGAOvarian Cancer21720365, 18772890
ENSP00000356331G95WCOSMICIntestines Cancer

Differential expressed protein
NR5A2_HUMAN is not differential expressed protein.

Hyperphosphorylation site
NR5A2_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
NR5A2_HUMANCP7A1_HUMANTF -> target geneTRANSFAC

Function Annotation
KEGG Pathway
NR5A2_HUMAN is not in KEGG pathway.

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0003677DNA bindingIDAmolecular_function
GO:0009790embryo developmentTASbiological_process
GO:0003705RNA polymerase II distal enhancer sequence-specifiTASmolecular_function
GO:0045070positive regulation of viral genome replicationIDAbiological_process
GO:0005515protein bindingIPImolecular_function
GO:0042592homeostatic processNASbiological_process
GO:0005654nucleoplasmTAScellular_component
GO:0043401steroid hormone mediated signaling pathwayIEAbiological_process
GO:0003690double-stranded DNA bindingIEAmolecular_function
GO:0008270zinc ion bindingIEAmolecular_function
GO:0010467gene expressionTASbiological_process
GO:0043565sequence-specific DNA bindingIEAmolecular_function
GO:0045944positive regulation of transcription from RNA polyIEAbiological_process
GO:0044212transcription regulatory region DNA bindingIDAmolecular_function
GO:0005737cytoplasmIDAcellular_component
GO:0003707steroid hormone receptor activityIEAmolecular_function
GO:0003677DNA bindingIEAmolecular_function
GO:0005634nucleusIEAcellular_component
GO:0042127regulation of cell proliferationIEAbiological_process
GO:0030522intracellular receptor mediated signaling pathwayIEAbiological_process
GO:0042632cholesterol homeostasisIEAbiological_process
GO:0005543phospholipid bindingIDAmolecular_function
GO:0006355regulation of transcription, DNA-dependentIDAbiological_process
GO:0045893positive regulation of transcription, DNA-dependenIDAbiological_process
GO:0003700sequence-specific DNA binding transcription factorIDAmolecular_function
GO:0008206bile acid metabolic processIEAbiological_process
GO:0006367transcription initiation from RNA polymerase II prTASbiological_process
GO:0004879ligand-activated sequence-specific DNA binding RNAIEAmolecular_function


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