Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:NPY1R_HUMAN
Description:neuropeptide Y receptor Y1 [Source:HGNC Symbol;Acc:7956]
Location:chr4 q32.2
Node attribute:receptor

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
T357MSTMHtDVSKTPhosphoSitePlus
S368SLKQAsPVAFKHPRD
S360MHTDVsKTSLKPhosphoSitePlus
T354TIAMStMHTDVPhosphoSitePlus
T349DDDYEtIAMSTPhosphoSitePlus
Y347SRDDDyETIAMPhosphoSitePlus

Dephosphorylation site
NPY1R_HUMAN do not have dephosphorylation site.

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000354652D346YCOSMICPancreatic Cancer
ENSP00000354652Q177KCOSMICHead and Neck Cancer21798893
ENSP00000354652A367GCOSMICHead and Neck Cancer21798893
ENSP00000354652F6YCOSMICLung Cancer20668451

Differential expressed protein
NPY1R_HUMAN is not differential expressed protein.

Hyperphosphorylation site
NPY1R_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
NPY_HUMANNPY1R_HUMANligand -> receptorHPMR
PYY2_HUMANNPY1R_HUMANligand -> receptorHPMR

Function Annotation
KEGG Pathway
KEGG IDPathway
hsa04080Neuroactive ligand-receptor interaction

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0004983neuropeptide Y receptor activityTASmolecular_function
GO:0007193adenylate cyclase-inhibiting G-protein coupled recTASbiological_process
GO:0003151outflow tract morphogenesisIMPbiological_process
GO:0008217regulation of blood pressureIEAbiological_process
GO:0006006glucose metabolic processIEAbiological_process
GO:0040014regulation of multicellular organism growthIEAbiological_process
GO:0005886plasma membraneTAScellular_component
GO:0001601peptide YY receptor activityIEAmolecular_function
GO:0005887integral to plasma membraneTAScellular_component
GO:0007186G-protein coupled receptor signaling pathwayIEAbiological_process
GO:0004930G-protein coupled receptor activityIEAmolecular_function
GO:0007626locomotory behaviorIEAbiological_process
GO:0016021integral to membraneIEAcellular_component
GO:0019233sensory perception of painIEAbiological_process
GO:0007631feeding behaviorIEAbiological_process
GO:0001602pancreatic polypeptide receptor activityIEAmolecular_function
GO:0004983neuropeptide Y receptor activityIEAmolecular_function
GO:0007187G-protein coupled receptor signaling pathway, coupTASbiological_process


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