Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:NCOR2_HUMAN
Description:nuclear receptor corepressor 2 [Source:HGNC Symbol;Acc:7673]
Location:chr12 q24.31
Node attribute:substrate

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
S753TESIPsPHTEAPhosphoSitePlus; HPRD; phosphoELM
S2204APARGsPHSEGHPRD
S2048ELELRsLGYHGPhosphoSitePlus
S373SEHEVsEIIDGPhosphoSitePlus
S1259IIGEDsPSRLDPhosphoSitePlus
T748NNSSDtESIPSHPRD; phosphoELM
S2197APARGsPHSEGphosphoELM; RegPhos
S2061VSPVSsPSLTHphosphoELM; RegPhos
T1444EELRHtPELPLPhosphoSitePlus
T1463SITQGtPLKYDPhosphoSitePlus
S1872QHSPIsPRTQDPhosphoSitePlus
S956PRANAsPQKPLPhosphoSitePlus; HPRD; phosphoELM; RegPhos
S2189LRRPPsDLYLPPhosphoSitePlus
S2464EDRPSsAGSTPPhosphoSitePlus
S2418VSGRPsSRKAKPhosphoSitePlus
S1214SVPGGsITKGIHPRD
S2462WEDRPsSAGSTHPRD
S2514QYETLsDphosphoELM
S2049HGSSYsPEGVEphosphoELM; RegPhos
S2069VSPVSsPSLTHPhosphoSitePlus
S1786SSSPLsPGGPTPhosphoSitePlus
S2524ETLSDsE____PhosphoSitePlus
S1539GKPRQsPLTYEphosphoELM; RegPhos
T1790SPGGPtHLTKPHPRD
S1181KQEQLsPRGQAPhosphoSitePlus
S1981LEPASsPSKGSHPRD
S2064GVEPVsPVSSPHPRD
S1209GTALGsVPGGSHPRD
S2213EGGKRsPEPNKHPRD
S2207RGSPHsEGGKRHPRD
T1824EKSILtSTTTVPhosphoSitePlus
S2514QYETLsDSERegPhos
S2057GVEPVsPVSSPphosphoELM; RegPhos
S2068VSPVSsPSLTHHPRD
S1258IIGEDsPSRLDHPRD
S2439PPSVSsVHSEGHPRD
S2234GIEPVsPPEGMPhosphoSitePlus
T553EKTDDtSGEDNPhosphoSitePlus; HPRD; phosphoELM; RegPhos
T2467SSAGStPFPYNHPRD
T1549RQSPLtYEDHGHPRD
S745ATVNNsSDTESHPRD; phosphoELM
T2402SDHTLtSPGGGHPRD
S1348PPERHsPHHLKHPRD
T1383LKREGtPPPPPphosphoELM; RegPhos
S2436GDRPPsVSSVHHPRD
T2239PPEGMtEPGHSHPRD
S1018QQPGSsPRGKSPhosphoSitePlus; phosphoELM; RegPhos
S2067PVSPVsSPSLTHPRD
S1980GLEPAsSPSKGHPRD
S1398PPPPPsRDLTEPhosphoSitePlus
S1016PQQPGsSPRGKHPRD
S2173PAPLYsFPGASPhosphoSitePlus
T1827ILTSTtTVEHAPhosphoSitePlus
S2233GIEPVsPPEGMHPRD
T1596RKLTStPREIAPhosphoSitePlus
S152PVSPPsPPHTDPhosphoSitePlus; HPRD; phosphoELM; RegPhos
S1486RSLIGsPGRTFHPRD
T1607KSPHStVPEHHPhosphoSitePlus
S1983PASSPsKGSEPHPRD
T946RPSLLtPTGDPPhosphoSitePlus; HPRD
S1349PPERHsPHHLKPhosphoSitePlus
S1260GEDSPsRLDRGHPRD
S1871QHSPIsPRTQDHPRD
T2519CSQYEtLSDHPRD
S2442VSSVHsEGDCNHPRD
T156PSPPHtDPELEPhosphoSitePlus; HPRD; phosphoELM; RegPhos
S1781SSRHSsSPLSPHPRD
S1025RGKSRsPAPPAPhosphoSitePlus
S2430APGLAsGDRPPHPRD
S1974KPPARsGLEPAHPRD
T1206SVLRGtALGSVPhosphoSitePlus
S1210GTALGsVPGGSPhosphoSitePlus
S1780FSSRHsSSPLSHPRD
T1391LKREGtPPPPPPhosphoSitePlus
S922SSATCsADEVDHPRD; phosphoELM
S2200RGSPHsEGGKRphosphoELM; RegPhos
S750SSDTEsIPSPHPhosphoSitePlus; HPRD; phosphoELM
T2073SSPSLtHDKGLPhosphoSitePlus
S149KLEPVsPPSPPPhosphoSitePlus; HPRD; phosphoELM; RegPhos
S2466PSSAGsTPFPYHPRD
T1793GPTHLtKPTTTHPRD
T2072SSPSLtHDKGLHPRD
S2438RPPSVsSVHSEHPRD
S2068PVSPVsSPSLTPhosphoSitePlus
S1331VGRAIsSASIEPhosphoSitePlus
S939KNRLLsPRPSLPhosphoSitePlus; HPRD; phosphoELM; RegPhos
S1487RSLIGsPGRTFPhosphoSitePlus
S1547GKPRQsPLTYEPhosphoSitePlus
S1583EGSLSsSKASQHPRD
S79PGNERsQELHLPhosphoSitePlus
S1975KPPARsGLEPAPhosphoSitePlus
S2125SQPSSsPLLQTPhosphoSitePlus
S2437GDRPPsVSSVHPhosphoSitePlus
Y2250SRSAVyPLLYRPhosphoSitePlus
S1581RLQEGsLSSSKPhosphoSitePlus
S2410VSGRPsSRKAKIKK_alphaphosphoELM
S2516ETLSDphosphoELM
S2269RMGSKsPGNTSPhosphoSitePlus
S2056HGSSYsPEGVEHPRD
S1862RPASHsHAHQHHPRD
S2416SRKAKsPAPGLphosphoELM; RegPhos
S1458PLKEGsITQGTPhosphoSitePlus
S2261RMGSKsPGNTSphosphoELM; RegPhos
S2521QYETLsDHPRD
S2266PSRMGsKSPGNHPRD
S1261GEDSPsRLDRGPhosphoSitePlus
S1580RLQEGsLSSSKHPRD
S2410VSGRPsSRKAKIKKa(IKK alphaRegPhos
S1602REIAKsPHSTVHPRD
S1783SRHSSsPLSPGPhosphoSitePlus
S2015APHHAsPDPPAHPRD
S2008APHHAsPDPPAphosphoELM; RegPhos
T1522KSRPGtASSSGPhosphoSitePlus
S2268RMGSKsPGNTSHPRD
S1546GKPRQsPLTYEHPRD
S1617HPHPIsPYEHLPhosphoSitePlus
T756IPSPHtEAAKDHPRD; phosphoELM
S2523ETLSDHPRD
T2468SSAGStPFPYNPhosphoSitePlus
S1024RGKSRsPAPPAHPRD
S2057HGSSYsPEGVEPhosphoSitePlus
S1334AISSAsIEGLMPhosphoSitePlus
Y1512LERACyEESLKPhosphoSitePlus
S67QRRRPsLLSEFPhosphoSitePlus; HPRD
S1982LEPASsPSKGSPhosphoSitePlus
Y2055YHGSSySPEGVHPRD
S1253GEDSPsRLDRGphosphoELM; RegPhos
S1868HAHQHsPISPRHPRD
S2403DHTLTsPGGGGHPRD
S2273SPGNTsQPPAFHPRD
T550LLKEKtDDTSGHPRD
S1017PQQPGsSPRGKphosphoELM; RegPhos
S215PEKPVsPPPIEPhosphoSitePlus; HPRD; phosphoELM; RegPhos
S2214EGGKRsPEPNKPhosphoSitePlus
S1008NLQPEsDAPQQHPRD
S1576EGSLSsSKASQphosphoELM; RegPhos
S1023SPRGKsRSPAPPhosphoSitePlus
S1332GRAISsASIEGPhosphoSitePlus
S1603REIAKsPHSTVPhosphoSitePlus
S2463EDRPSsAGSTPHPRD
S2065GVEPVsPVSSPPhosphoSitePlus
T741CSGPAtVNNSSPhosphoSitePlus
S2054GYHGSsYSPEGHPRD
S1860SSRPAsHSHAHHPRD
S1981GLEPAsSPSKGPhosphoSitePlus
S54YASHLsPGSIIPhosphoSitePlus; HPRD; phosphoELM
T2272KSPGNtSQPPAHPRD
S1017QQPGSsPRGKSHPRD
S2274SPGNTsQPPAFPhosphoSitePlus
S2053LGYHGsSYSPEHPRD
S1022SPRGKsRSPAPHPRD
S1869HAHQHsPISPRPhosphoSitePlus
S1974LEPASsPSKGSphosphoELM; RegPhos
S1778SSSPLsPGGPTphosphoELM; RegPhos
Y333KVREYyEKQFPPhosphoSitePlus
S2024PAPPAsASDPHHPRD
T2273KSPGNtSQPPAPhosphoSitePlus
S2522QYETLsDSE__PhosphoSitePlus
S2431APGLAsGDRPPPhosphoSitePlus
S1483KHDVRsLIGSPPhosphoSitePlus
S2455WEDRPsSAGSTRegPhos
Y2050LRSLGyHGSSYHPRD
Y1278KGHVIyEGKKGPhosphoSitePlus
T1390LKREGtPPPPPHPRD
S2070PVSSPsLTHDKHPRD
S554KTDDTsGEDNDPhosphoSitePlus; HPRD; phosphoELM; RegPhos
S2516ETLSDsERegPhos
S1821REREKsILTSTPhosphoSitePlus
S746TVNNSsDTESIHPRD; phosphoELM
Y332SKVREyYEKQFPhosphoSitePlus
T1205SVLRGtALGSVHPRD
S943LSPRPsLLTPTPhosphoSitePlus; HPRD
S2016APHHAsPDPPAPhosphoSitePlus
S1626LLRGVsGVDLYHPRD
S1785SSSPLsPGGPTHPRD
Y2172LPAPLySFPGAPhosphoSitePlus
Y1378EAQEDyLRREAPhosphoSitePlus
S1227STRVPsDSAITPhosphoSitePlus
S1782SRHSSsPLSPGHPRD
S221PPPIEsKHRSLHPRD

Dephosphorylation site
NCOR2_HUMAN do not have dephosphorylation site.

Mutation site
NCOR2_HUMAN do not have mutation site.

Differential expressed protein
NCOR2_HUMAN is not differential expressed protein.

Hyperphosphorylation site
NCOR2_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
ZAGL2_HUMANNCOR2_HUMANkinase -> substrateRegPhos

Function Annotation
KEGG Pathway
KEGG IDPathway
hsa04330Notch signaling pathway
hsa05169Epstein-Barr virus infection

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0005515protein bindingIPImolecular_function
GO:0000122negative regulation of transcription from RNA polyIEAbiological_process
GO:0006367transcription initiation from RNA polymerase II prTASbiological_process
GO:0021537telencephalon developmentIEAbiological_process
GO:0060206estrous cycle phaseIEAbiological_process
GO:0017053transcriptional repressor complexIDAcellular_component
GO:0044281small molecule metabolic processTASbiological_process
GO:0047485protein N-terminus bindingIPImolecular_function
GO:0010467gene expressionTASbiological_process
GO:0035259glucocorticoid receptor bindingIEAmolecular_function
GO:0005112Notch bindingIPImolecular_function
GO:0016922ligand-dependent nuclear receptor bindingIEAmolecular_function
GO:0003007heart morphogenesisIEAbiological_process
GO:0005634nucleusIDAcellular_component
GO:0016604nuclear bodyIEAcellular_component
GO:0001012RNA polymerase II regulatory region DNA bindingIEAmolecular_function
GO:0042593glucose homeostasisIEAbiological_process
GO:0007179transforming growth factor beta receptor signalingTASbiological_process
GO:0072365regulation of cellular ketone metabolic process byIMPbiological_process
GO:0050872white fat cell differentiationIEAbiological_process
GO:0005654nucleoplasmTAScellular_component
GO:0000118histone deacetylase complexIEAcellular_component
GO:0042826histone deacetylase bindingIPImolecular_function
GO:0000785chromatinIEAcellular_component
GO:0003714transcription corepressor activityIEAmolecular_function
GO:0003677DNA bindingIEAmolecular_function
GO:0032355response to estradiol stimulusIEAbiological_process
GO:0044255cellular lipid metabolic processTASbiological_process
GO:0007595lactationIEAbiological_process
GO:0046965retinoid X receptor bindingIEAmolecular_function
GO:0006351transcription, DNA-dependentTASbiological_process
GO:0045599negative regulation of fat cell differentiationIEAbiological_process
GO:0007219Notch signaling pathwayTASbiological_process
GO:0003682chromatin bindingIEAmolecular_function
GO:0043565sequence-specific DNA bindingIEAmolecular_function
GO:0021846cell proliferation in forebrainIEAbiological_process
GO:0010243response to organic nitrogenIEAbiological_process
GO:0032403protein complex bindingIEAmolecular_function
GO:0001701in utero embryonic developmentIEAbiological_process


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