| UniProt/SwissProt ID: | MTLR_HUMAN |
| Description: | motilin receptor [Source:HGNC Symbol;Acc:4495] |
| Location: | chr13 q14.2 |
| Node attribute: | receptor; PPI(target) |
| Phosphorylation site |
| Position | PhosphoPeptide | Catalytic kinase | Source |
|---|---|---|---|
| T296 | RGHRQtVRVLL | 7tm_1 | PhosphoSitePlus |
| T73 | DMRTTtNLYLG | 7tm_1 | PhosphoSitePlus |
| T404 | VGYTEtSANVK | PhosphoSitePlus | |
| T72 | RDMRTtTNLYL | 7tm_1 | PhosphoSitePlus |
| T402 | DTVGYtETSAN | PhosphoSitePlus | |
| S327 | INTEDsRMMYF | 7tm_1 | PhosphoSitePlus |
| T398 | DTGGDtVGYTE | HPRD | |
| T324 | IIYINtEDSRM | 7tm_1 | PhosphoSitePlus |
| T71 | YRDMRtTTNLY | 7tm_1 | PhosphoSitePlus |
| Dephosphorylation site |
| MTLR_HUMAN do not have dephosphorylation site. |
| Mutation site |
| Ensembl ID | Variation | Source | Cancer name | Pubmed |
|---|---|---|---|---|
| ENSP00000218721 | P280L | COSMIC | Ovarian Cancer | 21720365 |
| Differential expressed protein |
| MTLR_HUMAN is not differential expressed protein. |
| Hyperphosphorylation site |
| MTLR_HUMAN do not have hyperphosphorylation site. |
| Direct Interaction Pair |
| Source | Target | Relationship | Resource |
|---|---|---|---|
| MOTI_HUMAN | MTLR_HUMAN | ligand -> receptor | HPMR |
| IP3KA_HUMAN | MTLR_HUMAN | other | KEGG |
| Function Annotation |
| KEGG Pathway |
| KEGG ID | Pathway |
|---|---|
| hsa04080 | Neuroactive ligand-receptor interaction |
| Gene Ontology |
| GO ID | GO_Term | Evidence | Ontology |
|---|---|---|---|
| GO:0016520 | growth hormone-releasing hormone receptor activity | IEA | molecular_function |
| GO:0007586 | digestion | TAS | biological_process |
| GO:0004930 | G-protein coupled receptor activity | TAS | molecular_function |
| GO:0007186 | G-protein coupled receptor signaling pathway | TAS | biological_process |
| GO:0005886 | plasma membrane | TAS | cellular_component |
| GO:0016021 | integral to membrane | IEA | cellular_component |
| GO:0005887 | integral to plasma membrane | TAS | cellular_component |