Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:MTG16_HUMAN
Description:core-binding factor, runt domain, alpha subunit 2; translocated to, 3 [Source:HGNC Symbol;Acc:1537]
Location:chr16 q24.3
Node attribute:substrate

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
S439WARRYsDAEDTNHR2PhosphoSitePlus
S459RPRSSsAGPEGPhosphoSitePlus; HPRD
S36SGLLAsAGCSAPhosphoSitePlus
S328PAQRYsPSNGPHPRD
S65SAMPDsPAEVKPhosphoSitePlus
S457AARPRsSSAGPPhosphoSitePlus
T337GPPQPtPPPHYPhosphoSitePlus
S629GAASPsEAGSAPhosphoSitePlus
S641PSRPGsPSPPGPhosphoSitePlus
T521AHELItTERAKPhosphoSitePlus
S458ARPRSsSAGPEPhosphoSitePlus
S373RPRSSsAGPEGHPRD
Y327NPAQRySPSNGPhosphoSitePlus
S242PAQRYsPSNGPHPRD

Dephosphorylation site
MTG16_HUMAN do not have dephosphorylation site.

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000268679E518KHPIColorectal Cancer16959974
ENSP00000268679E554KCOSMICOvarian Cancer20668451
ENSP00000268679R306HHPIColorectal Cancer16959974
ENSP00000268679R306HSjoblom2006, COSMICIntestines Cancer16959974
ENSP00000268679A534VSjoblom2006, COSMICIntestines Cancer16959974
ENSP00000268679E518KSjoblom2006, COSMICIntestines Cancer16959974
ENSP00000268679A534VHPIColorectal Cancer16959974
ENSP00000268679D297fs*25COSMICHead and Neck Cancer21798893

Differential expressed protein
MTG16_HUMAN is not differential expressed protein.

Hyperphosphorylation site
MTG16_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
RET_HUMANMTG16_HUMANkinase -> substrateRobert H Newman (2013)
KPCA_HUMANMTG16_HUMANkinase -> substrateRobert H Newman (2013)

Function Annotation
KEGG Pathway
MTG16_HUMAN is not in KEGG pathway.

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0005730nucleolusIEAcellular_component
GO:0000139Golgi membraneIEAcellular_component
GO:0005515protein bindingIEAmolecular_function
GO:0006355regulation of transcription, DNA-dependentIEAbiological_process
GO:0008270zinc ion bindingIEAmolecular_function
GO:0005622intracellularIEAcellular_component
GO:0003700sequence-specific DNA binding transcription factorIEAmolecular_function
GO:0005654nucleoplasmIEAcellular_component
GO:0045944positive regulation of transcription from RNA polyIEAbiological_process
GO:0030851granulocyte differentiationIDAbiological_process
GO:0005515protein bindingIPImolecular_function
GO:0003682chromatin bindingIEAmolecular_function
GO:0006351transcription, DNA-dependentIEAbiological_process
GO:0008283cell proliferationTASbiological_process


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