Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:LYAM3_HUMAN
Description:selectin P (granule membrane protein 140kDa, antigen CD62) [Source:HGNC Symbol;Acc:10721]
Location:chr1 q24.2
Node attribute:gene

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
S813PLNPHsHLGTYPhosphoSitePlus; phosphoELM
T817HSHLGtYGVFTPhosphoSitePlus; phosphoELM
T822TYGVFtNAAFDPhosphoSitePlus; phosphoELM
S829AAFDPsP____PhosphoSitePlus
Y818SHLGTyGVFTNPhosphoSitePlus
S829AAFDPphosphoELM

Dephosphorylation site
LYAM3_HUMAN do not have dephosphorylation site.

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000263686C510*BIOMARTBreast Cancer21930507, 21930502
ENSP00000356764E750GCOSMICMelanoma21499247
ENSP00000356764R556*COSMICMelanoma21499247
ENSP00000356764T782KCOSMICHead and Neck Cancer21798893
ENSP00000356764L217MCOSMICOvarian Cancer21720365
ENSP00000356764S596TCOSMICOvarian Cancer21720365
ENSP00000356764C510*BIOMARTBreast Cancer21930507, 21930502

Differential expressed protein
LYAM3_HUMAN is not differential expressed protein.

Hyperphosphorylation site
LYAM3_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
GATA2_HUMANLYAM3_HUMANTF -> target geneTRANSFAC

Function Annotation
KEGG Pathway
LYAM3_HUMAN is not in KEGG pathway.

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0006954inflammatory responseIEAbiological_process
GO:0031092platelet alpha granule membraneIDAcellular_component
GO:0005886plasma membraneTAScellular_component
GO:0007159leukocyte cell-cell adhesionIDAbiological_process
GO:0007159leukocyte cell-cell adhesionIEAbiological_process
GO:0050900leukocyte migrationIEAbiological_process
GO:0016020membraneIEAcellular_component
GO:0070492oligosaccharide bindingIDAmolecular_function
GO:0007157heterophilic cell-cell adhesionIEAbiological_process
GO:0042806fucose bindingIDAmolecular_function
GO:0031088platelet dense granule membraneTAScellular_component
GO:0007596blood coagulationTASbiological_process
GO:0010572positive regulation of platelet activationIEAbiological_process
GO:0050901leukocyte tethering or rollingIEAbiological_process
GO:0030246carbohydrate bindingIEAmolecular_function
GO:0050829defense response to Gram-negative bacteriumICbiological_process
GO:0050900leukocyte migrationTASbiological_process
GO:0008201heparin bindingIDAmolecular_function
GO:0001530lipopolysaccharide bindingIMPmolecular_function
GO:0033691sialic acid bindingIEAmolecular_function
GO:0030168platelet activationTASbiological_process
GO:0005887integral to plasma membraneTAScellular_component
GO:0005615extracellular spaceIDAcellular_component
GO:0048306calcium-dependent protein bindingIEAmolecular_function
GO:0005634nucleusIDAcellular_component
GO:0033623regulation of integrin activationIMPbiological_process
GO:0002576platelet degranulationTASbiological_process
GO:0001948glycoprotein bindingIEAmolecular_function
GO:0005515protein bindingIEAmolecular_function
GO:0005515protein bindingIPImolecular_function
GO:0014068positive regulation of phosphatidylinositol 3-kinaIDAbiological_process
GO:0009897external side of plasma membraneIEAcellular_component
GO:0005737cytoplasmIDAcellular_component
GO:0002687positive regulation of leukocyte migrationIEAbiological_process
GO:0043208glycosphingolipid bindingTASmolecular_function
GO:0032496response to lipopolysaccharideICbiological_process
GO:0007155cell adhesionTASbiological_process


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