| UniProt/SwissProt ID: | LARP6_HUMAN |
| Description: | La ribonucleoprotein domain family, member 6 [Source:HGNC Symbol;Acc:24012] |
| Location: | chr15 q23 |
| Node attribute: | substrate |
| Phosphorylation site |
| Position | PhosphoPeptide | Catalytic kinase | Source |
|---|---|---|---|
| S447 | GTQEKsPGTSP | PhosphoSitePlus; HPRD | |
| S128 | KLGYVsVKLLT | La | PhosphoSitePlus |
| S56 | SPGWGsASEEE | PhosphoSitePlus; HPRD | |
| S455 | TSPLLsRKMQT | PhosphoSitePlus | |
| T133 | SVKLLtSFKKV | La | PhosphoSitePlus |
| S451 | KSPGTsPLLSR | PhosphoSitePlus; HPRD | |
| S58 | GWGSAsEEEPS | PhosphoSitePlus; HPRD | |
| S409 | LNCSTsPEIFR | PhosphoSitePlus; HPRD | |
| Dephosphorylation site |
| LARP6_HUMAN do not have dephosphorylation site. |
| Mutation site |
| Ensembl ID | Variation | Source | Cancer name | Pubmed |
|---|---|---|---|---|
| ENSP00000299213 | P241S | COSMIC | Skin Cancer | 21984974 | ENSP00000299213 | Q281* | COSMIC | Head and Neck Cancer | 21798893 |
| Differential expressed protein |
| LARP6_HUMAN is not differential expressed protein. |
| Hyperphosphorylation site |
| LARP6_HUMAN do not have hyperphosphorylation site. |
| Direct Interaction Pair |
| Source | Target | Relationship | Resource |
|---|---|---|---|
| DYRK2_HUMAN | LARP6_HUMAN | kinase -> substrate | Robert H Newman (2013) |
| FGFR2_HUMAN | LARP6_HUMAN | kinase -> substrate | Robert H Newman (2013) |
| Function Annotation |
| KEGG Pathway |
| LARP6_HUMAN is not in KEGG pathway. |
| Gene Ontology |
| GO ID | GO_Term | Evidence | Ontology |
|---|---|---|---|
| GO:0005794 | Golgi apparatus | IDA | cellular_component |
| GO:0006396 | RNA processing | IEA | biological_process |
| GO:0043231 | intracellular membrane-bounded organelle | IDA | cellular_component |
| GO:0006417 | regulation of translation | IEA | biological_process |
| GO:0003723 | RNA binding | IEA | molecular_function |
| GO:0005634 | nucleus | IDA | cellular_component |
| GO:0030529 | ribonucleoprotein complex | IEA | cellular_component |
| GO:0000166 | nucleotide binding | IEA | molecular_function |