Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:KREM1_HUMAN
Description:kringle containing transmembrane protein 1 [Source:HGNC Symbol;Acc:17550]
Location:chr22 q12.1
Node attribute:receptor

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
T341VAEVItEQANLPhosphoSitePlus
T335PAVNQtVAEVIPhosphoSitePlus

Dephosphorylation site
KREM1_HUMAN do not have dephosphorylation site.

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000385431R277HBIOMARTBreast Cancer21930507, 21930502
ENSP00000383189R279HBIOMARTBreast Cancer21930507, 21930502
ENSP00000331242E182KCOSMICHead and Neck Cancer21984974
ENSP00000331242A339SCOSMICLung Cancer20668451
ENSP00000331242V93LCOSMICLung Cancer
ENSP00000331242R279HBIOMARTBreast Cancer21930507, 21930502
ENSP00000331242S421FCOSMICOvarian Cancer21720365
ENSP00000385431*474GCOSMICOvarian Cancer21720365
ENSP00000331242G217RCOSMICOvarian Cancer20668451

Differential expressed protein
KREM1_HUMAN is not differential expressed protein.

Hyperphosphorylation site
KREM1_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
DKK1_HUMANKREM1_HUMANligand -> receptorHPMR

Function Annotation
KEGG Pathway
KREM1_HUMAN is not in KEGG pathway.

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0005515protein bindingIPImolecular_function
GO:0016020membraneTAScellular_component
GO:0060828regulation of canonical Wnt receptor signaling patNASbiological_process
GO:0016055Wnt receptor signaling pathwayIEAbiological_process
GO:0016021integral to membraneIEAcellular_component
GO:0007154cell communicationTASbiological_process


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