Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:KPCD3_HUMAN
Description:protein kinase D3 [Source:HGNC Symbol;Acc:9408]
Location:chr2 p22.2
Node attribute:kinase

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
S252SKRIPsWSGRPPhosphoSitePlus; HPRD; SysPTM
S41LSARLsNGSFSPhosphoSitePlus; HPRD; phosphoELM; SysPTM
S44RLSNGsFSAPSPhosphoSitePlus; HPRD; phosphoELM
T389EEAVKtISPSTPhosphoSitePlus
S395ISPSTsNNIPLPhosphoSitePlus; HPRD
S37PKTGLsARLSNPhosphoSitePlus; HPRD
S247VHQEPsKRIPSHPRD
S254RIPSWsGRPIWPhosphoSitePlus
S731IIGEKsFRRSVHPRD; phosphoELM
S216RLSNVsLPGPGPhosphoSitePlus; HPRD; SysPTM
S735KSFRRsVVGTPPkinasePhosphoSitePlus; SysPTM
S30AASPCsSPKTGPhosphoSitePlus; HPRD; phosphoELM
S213RKRRLsNVSLPPhosphoSitePlus; HPRD; SysPTM
S6MSANNsPPSAQPhosphoSitePlus; SysPTM
Y742VGTPAyLAPEVPkinasePhosphoSitePlus
S223PGPGLsVPRPLHPRD
S237YVALPsEESHVHPRD
S2____MsANNSPPhosphoSitePlus
S415TKRKSsTMVKEPhosphoSitePlus
Y867WEIHAyTHNLVPhosphoSitePlus
S13PSAQKsVLPTAHPRD
T739RSVVGtPAYLAHPRD
S391AVKTIsPSTSNPhosphoSitePlus; HPRD; phosphoELM; SysPTM
S543ASVCTsPGQGKPhosphoSitePlus; HPRD; SysPTM
T542QASVCtSPGQGHPRD
S393KTISPsTSNNIHPRD
S539VTPQAsVCTSPHPRD
S31ASPCSsPKTGLPhosphoSitePlus; HPRD; phosphoELM
S364DTEEPsPPEDKPhosphoSitePlus; HPRD; phosphoELM; SysPTM
S735KSFRRsVVGTPHPRD; phosphoELM; SysPTM
T535ALMPVtPQASVPhosphoSitePlus; HPRD; SysPTM
S731IIGEKsFRRSVPkinasePhosphoSitePlus
S6PSAQHPRD; SysPTM
Y852RIGERyITHESPhosphoSitePlus
S9NNSPPsAQKSVHPRD
S27VLPAAsPCSSPPhosphoSitePlus; HPRD; phosphoELM

Dephosphorylation site
KPCD3_HUMAN do not have dephosphorylation site.

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000368356L687FBIOMARTBreast Cancer21930507, 21930502
ENSP00000234179V716MGreenman2007Central Nervous System Neoplasms16618716, 17344846, 18428421
ENSP00000234179V716MGreenman2007, HPINeoplasms by Histologic Type16618716, 17344846, 18428421
ENSP00000368356R211CDing2008Lung Cancer18948947
ENSP00000234179E231DBIOMARTBreast Cancer21930507, 21930502
ENSP00000368356L812MCOSMICOvarian Cancer21720365
ENSP00000368356R211CBIOMARTLung Cancer21930507, 21930502
ENSP00000234179R211CDing2008Lung Cancer18948947
ENSP00000368356E231DBIOMARTBreast Cancer21930507, 21930502
ENSP00000234179L687FBIOMARTBreast Cancer21930507, 21930502
ENSP00000368356V716MGreenman2007, HPINeoplasms by Histologic Type16618716, 17344846, 18428421
ENSP00000368356P236LDing2008, BIOMARTLung Cancer18948947, 21930507, 21930502
ENSP00000368356F307SCOSMICOvarian Cancer21720365
ENSP00000234179P236LDing2008Lung Cancer18948947
ENSP00000368356V716MGreenman2007Central Nervous System Neoplasms16618716, 17344846, 18428421

Differential expressed protein
KPCD3_HUMAN is not differential expressed protein.

Hyperphosphorylation site
KPCD3_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
KPCD3_HUMANGSK3A_HUMANkinase -> substrateHPRD

Function Annotation
KEGG Pathway
KPCD3_HUMAN is not in KEGG pathway.

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0005515protein bindingIPImolecular_function
GO:0005515protein bindingIEAmolecular_function
GO:0005634nucleusIDAcellular_component
GO:0042802identical protein bindingIPImolecular_function
GO:0007205protein kinase C-activating G-protein coupled receTASbiological_process
GO:0006468protein phosphorylationTASbiological_process
GO:0005737cytoplasmIDAcellular_component
GO:0016772transferase activity, transferring phosphorus-contIEAmolecular_function
GO:0005524ATP bindingIEAmolecular_function
GO:0035556intracellular signal transductionIEAbiological_process
GO:0004672protein kinase activityIEAmolecular_function
GO:0009103lipopolysaccharide biosynthetic processIEAbiological_process
GO:0004697protein kinase C activityIEAmolecular_function
GO:0016773phosphotransferase activity, alcohol group as acceIEAmolecular_function
GO:0004713protein tyrosine kinase activityIEAmolecular_function
GO:0046872metal ion bindingIEAmolecular_function
GO:0016020membraneIEAcellular_component
GO:0005543phospholipid bindingIEAmolecular_function


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