| UniProt/SwissProt ID: | KLRD1_HUMAN |
| Description: | killer cell lectin-like receptor subfamily D, member 1 [Source:HGNC Symbol;Acc:6378] |
| Location: | chr12 p13.2 |
| Node attribute: | receptor |
| Phosphorylation site |
| Position | PhosphoPeptide | Catalytic kinase | Source |
|---|---|---|---|
| S13 | LWRLIsGTLGI | TM | PhosphoSitePlus |
| T15 | RLISGtLGIIC | TM | PhosphoSitePlus |
| Dephosphorylation site |
| KLRD1_HUMAN do not have dephosphorylation site. |
| Mutation site |
| Ensembl ID | Variation | Source | Cancer name | Pubmed |
|---|---|---|---|---|
| ENSP00000338130 | A2P | COSMIC | Head and Neck Cancer | 21798893 | ENSP00000338130 | N148S | COSMIC | Head and Neck Cancer | 21798893 |
| Differential expressed protein |
| KLRD1_HUMAN is not differential expressed protein. |
| Hyperphosphorylation site |
| KLRD1_HUMAN do not have hyperphosphorylation site. |
| Direct Interaction Pair |
| Source | Target | Relationship | Resource |
|---|---|---|---|
| HLAG_HUMAN | KLRD1_HUMAN | ligand -> receptor | HPMR |
| Function Annotation |
| KEGG Pathway |
| KEGG ID | Pathway |
|---|---|
| hsa04612 | Antigen processing and presentation |
| hsa04650 | Natural killer cell mediated cytotoxicity |
| hsa05332 | Graft-versus-host disease |
| Gene Ontology |
| GO ID | GO_Term | Evidence | Ontology |
|---|---|---|---|
| GO:0009897 | external side of plasma membrane | IEA | cellular_component |
| GO:0007166 | cell surface receptor signaling pathway | TAS | biological_process |
| GO:0050776 | regulation of immune response | TAS | biological_process |
| GO:0030246 | carbohydrate binding | IEA | molecular_function |
| GO:0016021 | integral to membrane | IEA | cellular_component |
| GO:0004888 | transmembrane signaling receptor activity | TAS | molecular_function |
| GO:0005886 | plasma membrane | TAS | cellular_component |