| UniProt/SwissProt ID: | IL25_HUMAN |
| Description: | interleukin 25 [Source:HGNC Symbol;Acc:13765] |
| Location: | chr14 q11.2 |
| Node attribute: | ligand; PPI(source) |
| Phosphorylation site |
| Position | PhosphoPeptide | Catalytic kinase | Source |
|---|---|---|---|
| Y92 | ISPWRyELDRD | IL17 | PhosphoSitePlus |
| Dephosphorylation site |
| IL25_HUMAN do not have dephosphorylation site. |
| Mutation site |
| Ensembl ID | Variation | Source | Cancer name | Pubmed |
|---|---|---|---|---|
| ENSP00000380417 | S114L | BIOMART | Breast Cancer | 21930507, 21930502 | ENSP00000328111 | S130L | BIOMART | Breast Cancer | 21930507, 21930502 |
| Differential expressed protein |
| IL25_HUMAN is not differential expressed protein. |
| Hyperphosphorylation site |
| IL25_HUMAN do not have hyperphosphorylation site. |
| Direct Interaction Pair |
| Source | Target | Relationship | Resource |
|---|---|---|---|
| IL25_HUMAN | I17RB_HUMAN | ligand -> receptor | HPMR |
| IL25_HUMAN | I17RB_HUMAN | other | KEGG |
| Function Annotation |
| KEGG Pathway |
| KEGG ID | Pathway |
|---|---|
| hsa04060 | Cytokine-cytokine receptor interaction |
| Gene Ontology |
| GO ID | GO_Term | Evidence | Ontology |
|---|---|---|---|
| GO:0009620 | response to fungus | IEA | biological_process |
| GO:0045944 | positive regulation of transcription from RNA poly | IEA | biological_process |
| GO:0016020 | membrane | NAS | cellular_component |
| GO:0008150 | biological_process | ND | biological_process |
| GO:0009624 | response to nematode | IEA | biological_process |
| GO:0030222 | eosinophil differentiation | IEA | biological_process |
| GO:0005125 | cytokine activity | IEA | molecular_function |
| GO:0030380 | interleukin-17E receptor binding | TAS | molecular_function |
| GO:0005615 | extracellular space | IEA | cellular_component |
| GO:0006954 | inflammatory response | IEA | biological_process |
| GO:0002437 | inflammatory response to antigenic stimulus | IEA | biological_process |
| GO:0005576 | extracellular region | IEA | cellular_component |