| UniProt/SwissProt ID: | IBP6_HUMAN |
| Description: | insulin-like growth factor binding protein 6 [Source:HGNC Symbol;Acc:5475] |
| Location: | chr12 q13.13 |
| Node attribute: | gene |
| Phosphorylation site |
| IBP6_HUMAN do not have phosphorylation site. |
| Dephosphorylation site |
| IBP6_HUMAN do not have dephosphorylation site. |
| Mutation site |
| Ensembl ID | Variation | Source | Cancer name | Pubmed |
|---|---|---|---|---|
| ENSP00000301464 | G194C | TCGA | Ovarian Cancer | 21720365, 18772890 | ENSP00000301464 | G194C | COSMIC | Ovarian Cancer | 21720365 | ENSP00000301464 | R199W | BIOMART | Pancreatic Cancer | 21930507, 21930502 |
| Differential expressed protein |
| IBP6_HUMAN is not differential expressed protein. |
| Hyperphosphorylation site |
| IBP6_HUMAN do not have hyperphosphorylation site. |
| Direct Interaction Pair |
| Source | Target | Relationship | Resource |
|---|---|---|---|
| GLI1_HUMAN | IBP6_HUMAN | TF -> target gene | TRANSFAC |
| Function Annotation |
| KEGG Pathway |
| IBP6_HUMAN is not in KEGG pathway. |
| Gene Ontology |
| GO ID | GO_Term | Evidence | Ontology |
|---|---|---|---|
| GO:0005794 | Golgi apparatus | IEA | cellular_component |
| GO:0005520 | insulin-like growth factor binding | IEA | molecular_function |
| GO:0031994 | insulin-like growth factor I binding | IEA | molecular_function |
| GO:0005576 | extracellular region | TAS | cellular_component |
| GO:0005737 | cytoplasm | IEA | cellular_component |
| GO:0008285 | negative regulation of cell proliferation | TAS | biological_process |
| GO:0005615 | extracellular space | IEA | cellular_component |
| GO:0007165 | signal transduction | NAS | biological_process |
| GO:0001558 | regulation of cell growth | IEA | biological_process |