Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:HPCA_HUMAN
Description:hippocalcin [Source:HGNC Symbol;Acc:5144]
Location:chr1 p35.1
Node attribute:substrate

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
S143MPEDEsTPEKRPhosphoSitePlus
Y115LDGNGyISREEefhandPhosphoSitePlus
S191DPSSAsQF___PhosphoSitePlus
T144PEDEStPEKRTPhosphoSitePlus
Y129IVQAIyKMVSSPhosphoSitePlus

Dephosphorylation site
HPCA_HUMAN do not have dephosphorylation site.

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000362566E120QCOSMICOvarian Cancer21720365
ENSP00000362566S93LCOSMICSkin Cancer21984974

Differential expressed protein
Ensembl IDCancer nameDesignSampleChangeRatioPubmed
ENSP00000362566Breast CancerNormal vs. Cancercell lineUp7.420198662
ENSP00000362566Breast CancerMetastasiscell lineDown0.2620198662

Hyperphosphorylation site
HPCA_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
KPCA_HUMANHPCA_HUMANkinase -> substrateRobert H Newman (2013)

Function Annotation
KEGG Pathway
HPCA_HUMAN is not in KEGG pathway.

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0003779actin bindingIDAmolecular_function
GO:0005509calcium ion bindingNASmolecular_function
GO:0005515protein bindingIEAmolecular_function
GO:0048839inner ear developmentIEAbiological_process


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