Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:HNRL1_HUMAN
Description:heterogeneous nuclear ribonucleoprotein U-like 1 [Source:HGNC Symbol;Acc:17011]
Location:chr19 q13.2
Node attribute:substrate

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
S718PPPSYsPARNPPhosphoSitePlus; HPRD; phosphoELM; SysPTM
S668GGGGYsQNRWGPhosphoSitePlus
S194DRRGRsPQPPAPhosphoSitePlus; HPRD; phosphoELM; SysPTM
S444IKHAAsNPSKKPhosphoSitePlus
S716PPPPPsYSPARPhosphoSitePlus; HPRD; phosphoELM; SysPTM
S152QGAPTsFLPPEPhosphoSitePlus
T109DDFDDtLVAIDHPRD
Y124ENESGyERRPLPhosphoSitePlus
S94DRRGRsPQPPAHPRD
T209DDFDDtLVAIDPhosphoSitePlus; HPRD; phosphoELM
T215LVAIDtYNCDLPhosphoSitePlus
Y137EQQQAyRPEMKPhosphoSitePlus
S649NRGGGsGGGGNPhosphoSitePlus; HPRD
T455YNILGtNAIMDPhosphoSitePlus
Y183NRGRGyFEHREPhosphoSitePlus
Y175SRKRPyEENRGPhosphoSitePlus
S616PPPPPsYSPARHPRD
S549NRGGGsGGGGNHPRD
S512TNVYGsAQRRKPhosphoSitePlus; HPRD; phosphoELM; SysPTM
Y617PPPPSySPARNHPRD
Y510DQTNVyGSAQRPhosphoSitePlus
Y111RQNQFyDTQVIPhosphoSitePlus
S687SNNRGsYNRAPPhosphoSitePlus
T151KQGAPtSFLPPPhosphoSitePlus
S412TNVYGsAQRRKHPRD
S159LPPEAsQLKPDPhosphoSitePlus
Y717PPPPSySPARNPhosphoSitePlus; HPRD
S618PPPSYsPARNPHPRD

Dephosphorylation site
HNRL1_HUMAN do not have dephosphorylation site.

Mutation site
HNRL1_HUMAN do not have mutation site.

Differential expressed protein
Ensembl IDCancer nameDesignSampleChangeRatioPubmed
ENSP00000375863Ovarian CancerTreatment (cisplatin-sensitive vs. cisplatin-resistant)cell lineDown0.5616319398

Hyperphosphorylation site
HNRL1_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
MK09_HUMANHNRL1_HUMANkinase -> substrateRobert H Newman (2013)

Function Annotation
KEGG Pathway
HNRL1_HUMAN is not in KEGG pathway.

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0010467gene expressionTASbiological_process
GO:0006355regulation of transcription, DNA-dependentIEAbiological_process
GO:0005634nucleusIDAcellular_component
GO:0005515protein bindingIPImolecular_function
GO:0003676nucleic acid bindingIEAmolecular_function
GO:0006351transcription, DNA-dependentIEAbiological_process
GO:0030529ribonucleoprotein complexIEAcellular_component
GO:0009615response to virusIEAbiological_process
GO:0006396RNA processingTASbiological_process
GO:0000398mRNA splicing, via spliceosomeTASbiological_process
GO:0008380RNA splicingTASbiological_process
GO:0005654nucleoplasmTAScellular_component
GO:0003723RNA bindingIEAmolecular_function
GO:0019899enzyme bindingIPImolecular_function


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