| UniProt/SwissProt ID: | FCG2B_HUMAN |
| Description: | Fc fragment of IgG, low affinity IIb, receptor (CD32) [Source:HGNC Symbol;Acc:3618] |
| Location: | chr1 q23.3 |
| Node attribute: | substrate |
| Phosphorylation site |
| Position | PhosphoPeptide | Catalytic kinase | Source |
|---|---|---|---|
| S293 | NTITYsLLMHP | PhosphoSitePlus; HPRD | |
| Y292 | ENTITySLLMH | BLK | HPRD; phosphoELM; RegPhos |
| Y292 | ENTITySLLMH | PhosphoSitePlus | |
| S274 | NTITYsLLMHP | HPRD | |
| Y273 | ENTITySLLMH | BLK | HPRD |
| Y273 | ENTITySLLMH | LYN | HPRD |
| Y292 | ENTITySLLMH | LYN | HPRD; RegPhos |
| Y291 | ENTITySLLMH | BLK | HPRD |
| Y292 | ENTITySLLMH | Lyn | phosphoELM; RegPhos |
| Y272 | ENTITySLLMH | BLK | HPRD |
| Y291 | ENTITySLLMH | LYN | HPRD |
| Y272 | ENTITySLLMH | LYN | HPRD |
| S273 | NTITYsLLMHP | HPRD | |
| S292 | NTITYsLLMHP | HPRD | |
| Dephosphorylation site |
| FCG2B_HUMAN do not have dephosphorylation site. |
| Mutation site |
| FCG2B_HUMAN do not have mutation site. |
| Differential expressed protein |
| FCG2B_HUMAN is not differential expressed protein. |
| Hyperphosphorylation site |
| FCG2B_HUMAN do not have hyperphosphorylation site. |
| Direct Interaction Pair |
| Source | Target | Relationship | Resource |
|---|---|---|---|
| LYN_HUMAN | FCG2B_HUMAN | kinase -> substrate | HPRD; RegPhos; Robert H Newman (2013) |
| BLK_HUMAN | FCG2B_HUMAN | kinase -> substrate | HPRD; RegPhos; Robert H Newman (2013) |
| Function Annotation |
| KEGG Pathway |
| KEGG ID | Pathway |
|---|---|
| hsa04666 | Fc gamma R-mediated phagocytosis |
| hsa05150 | Staphylococcus aureus infection |
| hsa05322 | Systemic lupus erythematosus |
| hsa05152 | Tuberculosis |
| hsa04662 | B cell receptor signaling pathway |
| hsa04145 | Phagosome |
| hsa05162 | Measles |
| hsa04380 | Osteoclast differentiation |
| Gene Ontology |
| GO ID | GO_Term | Evidence | Ontology |
|---|---|---|---|
| GO:0050776 | regulation of immune response | TAS | biological_process |
| GO:0019864 | IgG binding | IEA | molecular_function |
| GO:0016021 | integral to membrane | IEA | cellular_component |
| GO:0019048 | virus-host interaction | IEA | biological_process |
| GO:0007165 | signal transduction | TAS | biological_process |
| GO:0006955 | immune response | TAS | biological_process |
| GO:0005515 | protein binding | IPI | molecular_function |
| GO:0005886 | plasma membrane | TAS | cellular_component |