| UniProt/SwissProt ID: | EIF3F_HUMAN |
| Description: | eukaryotic translation initiation factor 3, subunit F [Source:HGNC Symbol;Acc:3275] |
| Location: | chr11 p15.4 |
| Node attribute: | substrate |
| Phosphorylation site |
| Position | PhosphoPeptide | Catalytic kinase | Source |
|---|---|---|---|
| S258 | MKTCFsPNRVI | MitMem_reg | PhosphoSitePlus |
| S46 | AAPASsSDPAA | CDK19 | HPRD |
| Y216 | MSIKAyVSTLM | HPRD | |
| T255 | DLIMKtCFSPN | MitMem_reg | PhosphoSitePlus |
| S46 | AAPASsSDPAA | PhosphoSitePlus | |
| T119 | ARVIGtLLGTV | JAB | PhosphoSitePlus |
| T255 | DLIMKtCFSPN | HPRD; phosphoELM | |
| S46 | AAPASsSDPAA | CDK11 | phosphoELM; RegPhos |
| S258 | MKTCFsPNRVI | HPRD; phosphoELM | |
| S267 | VIGLSsDLQQV | MitMem_reg | PhosphoSitePlus |
| T233 | MGVMFtPLTVK | PhosphoSitePlus | |
| S266 | RVIGLsSDLQQ | MitMem_reg | PhosphoSitePlus |
| Y241 | TVKYAyYDTER | PhosphoSitePlus | |
| S105 | ASIVDsYERRN | JAB | PhosphoSitePlus |
| Dephosphorylation site |
| EIF3F_HUMAN do not have dephosphorylation site. |
| Mutation site |
| Ensembl ID | Variation | Source | Cancer name | Pubmed |
|---|---|---|---|---|
| ENSP00000310040 | V304L | COSMIC | Lung Cancer | 20668451 |
| Differential expressed protein |
| EIF3F_HUMAN is not differential expressed protein. |
| Hyperphosphorylation site |
| EIF3F_HUMAN do not have hyperphosphorylation site. |
| Direct Interaction Pair |
| Source | Target | Relationship | Resource |
|---|---|---|---|
| CDK19_HUMAN | EIF3F_HUMAN | kinase -> substrate | HPRD; RegPhos |
| Function Annotation |
| KEGG Pathway |
| KEGG ID | Pathway |
|---|---|
| hsa03013 | RNA transport |
| Gene Ontology |
| GO ID | GO_Term | Evidence | Ontology |
|---|---|---|---|
| GO:0005829 | cytosol | TAS | cellular_component |
| GO:0010467 | gene expression | TAS | biological_process |
| GO:0044267 | cellular protein metabolic process | TAS | biological_process |
| GO:0008234 | cysteine-type peptidase activity | IEA | molecular_function |
| GO:0006413 | translational initiation | IC | biological_process |
| GO:0005852 | eukaryotic translation initiation factor 3 complex | IEA | cellular_component |
| GO:0006508 | proteolysis | IEA | biological_process |
| GO:0003743 | translation initiation factor activity | IEA | molecular_function |
| GO:0006413 | translational initiation | IEA | biological_process |
| GO:0005515 | protein binding | IPI | molecular_function |
| GO:0006412 | translation | TAS | biological_process |