Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:DDX20_HUMAN
Description:DEAD (Asp-Glu-Ala-Asp) box polypeptide 20 [Source:HGNC Symbol;Acc:2743]
Location:chr1 p13.2
Node attribute:substrate

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
S654SGDSEsDSDSYPhosphoSitePlus; HPRD; phosphoELM
S742NLPRRsSFRLQPhosphoSitePlus
Y587KIHQPyTLTFAPhosphoSitePlus
S502RNNSVsGLSVKHPRD
Y711PNPEKyQESPGPhosphoSitePlus
Y770SFSDTyQDYEEPhosphoSitePlus
S268FVRLNsSDPSLPhosphoSitePlus; HPRD
T688KDSEStPVDDRPhosphoSitePlus; HPRD
S672SKGNKsYLEGSPhosphoSitePlus; HPRD; phosphoELM
T552KNSVQtPVENSPhosphoSitePlus; HPRD; phosphoELM
S500SSRNNsVSGLSPhosphoSitePlus; HPRD; phosphoELM
S48AQDLSsPRTRTPhosphoSitePlus; HPRD; phosphoELM
S532IEKATsPKELGPhosphoSitePlus; HPRD; phosphoELM
S678YLEGSsDNQLKPhosphoSitePlus; HPRD; phosphoELM
S505SVSGLsVKSKNPhosphoSitePlus
T705PNGSDtPNPEKPhosphoSitePlus; HPRD; phosphoELM
S765REIRLsFSDTYPhosphoSitePlus
Y462AAVHTyGIASVPhosphoSitePlus
S743LPRRSsFRLQTPhosphoSitePlus; phosphoELM
S649ASSSQsGDSESPhosphoSitePlus; HPRD; phosphoELM
S656DSESDsDSYSSPhosphoSitePlus; HPRD; phosphoELM
Y616EIIRHyTGPGDPhosphoSitePlus
S557TPVENsTNSQHHPRD
S86GFERPsPVQLKPhosphoSitePlus; HPRD
S685NQLKDsESTPVPhosphoSitePlus
Y673KGNKSyLEGSSPhosphoSitePlus; HPRD
T461KAAVHtYGIASPhosphoSitePlus
S703QPPNGsDTPNPPhosphoSitePlus; HPRD; phosphoELM
Y756QEDDWyDCHREPhosphoSitePlus
S47TAQDLsSPRTRHPRD
S187HIAVGsPGRIKDEADPhosphoSitePlus
S560ENSTNsQHQVKPhosphoSitePlus; HPRD
S442PDPIPsGLMEEPhosphoSitePlus
S187HIAVGsPGRIKHPRD
S272NSSDPsLIGLKPhosphoSitePlus; HPRD
S652SQSGDsESDSDPhosphoSitePlus; HPRD; phosphoELM
S677SYLEGsSDNQLPhosphoSitePlus; HPRD; phosphoELM
S549EQMKNsVQTPVHPRD
S714EKYQEsPGIQMPhosphoSitePlus; HPRD; phosphoELM
S542GCDRQsEEQMKPhosphoSitePlus

Dephosphorylation site
DDX20_HUMAN do not have dephosphorylation site.

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000358716D55YCOSMICLung Cancer20016488
ENSP00000358716A351SBIOMARTPancreatic Cancer21930507, 21930502
ENSP00000358716L536VCOSMICRenal Cancer20054297

Differential expressed protein
DDX20_HUMAN is not differential expressed protein.

Hyperphosphorylation site
DDX20_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
ILK_HUMANDDX20_HUMANkinase -> substrateRobert H Newman (2013)

Function Annotation
KEGG Pathway
DDX20_HUMAN is not in KEGG pathway.

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0005515protein bindingIEAmolecular_function
GO:0043065positive regulation of apoptotic processIEAbiological_process
GO:0000122negative regulation of transcription from RNA polyIEAbiological_process
GO:0005737cytoplasmIDAcellular_component
GO:0000387spliceosomal snRNP assemblyTASbiological_process
GO:0005524ATP bindingIEAmolecular_function
GO:0003677DNA bindingIEAmolecular_function
GO:0006917induction of apoptosisIEAbiological_process
GO:0010467gene expressionTASbiological_process
GO:0005515protein bindingIPImolecular_function
GO:0016070RNA metabolic processTASbiological_process
GO:0004386helicase activityIEAmolecular_function
GO:0043065positive regulation of apoptotic processISSbiological_process
GO:0034660ncRNA metabolic processTASbiological_process
GO:0006396RNA processingTASbiological_process
GO:0017053transcriptional repressor complexIEAcellular_component
GO:0005856cytoskeletonTAScellular_component
GO:0004004ATP-dependent RNA helicase activityTASmolecular_function
GO:0005654nucleoplasmTAScellular_component
GO:0000244assembly of spliceosomal tri-snRNPTASbiological_process
GO:0005681spliceosomal complexIEAcellular_component
GO:0008026ATP-dependent helicase activityIEAmolecular_function
GO:0003676nucleic acid bindingIEAmolecular_function
GO:0005634nucleusIDAcellular_component
GO:0015030Cajal bodyIEAcellular_component
GO:0005829cytosolTAScellular_component


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