Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:CXCL7_HUMAN
Description:pro-platelet basic protein (chemokine (C-X-C motif) ligand 7) [Source:HGNC Symbol;Acc:9240]
Location:chr4 q13.3
Node attribute:ligand; PPI(source)

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
Y58LDSDLyAELRCIL8PhosphoSitePlus

Dephosphorylation site
CXCL7_HUMAN do not have dephosphorylation site.

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000296028Q40KCOSMICOvarian Cancer21720365
ENSP00000296028G39ECOSMICMelanoma21499247
ENSP00000296028V92ICOSMICCentral Nervous System Neoplasms18772396
ENSP00000296028K114NBIOMARTBreast Cancer21930507, 21930502
ENSP00000296028G48VCOSMICOvarian Cancer21720365

Differential expressed protein
Ensembl IDCancer nameDesignSampleChangeRatioPubmed
ENSP00000296028acute lymphocytic leukemiaNormal vs. CancertissueDown19291297

Hyperphosphorylation site
CXCL7_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
CXCL7_HUMANCXCR2_HUMANligand -> receptorHPMR
CXCL7_HUMANCXCR2_HUMANotherKEGG

Function Annotation
KEGG Pathway
KEGG IDPathway
hsa04062Chemokine signaling pathway
hsa04060Cytokine-cytokine receptor interaction

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0008009chemokine activityIEAmolecular_function
GO:0005355glucose transmembrane transporter activityTASmolecular_function
GO:0015758glucose transportTASbiological_process
GO:0030168platelet activationTASbiological_process
GO:0005576extracellular regionTAScellular_component
GO:0005615extracellular spaceIEAcellular_component
GO:0031093platelet alpha granule lumenTAScellular_component
GO:0008083growth factor activityIEAmolecular_function
GO:0051781positive regulation of cell divisionIEAbiological_process
GO:0002576platelet degranulationTASbiological_process
GO:0006955immune responseIEAbiological_process
GO:0006935chemotaxisIEAbiological_process
GO:0007596blood coagulationTASbiological_process
GO:0042742defense response to bacteriumIEAbiological_process


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