| UniProt/SwissProt ID: | CXB1_HUMAN |
| Description: | gap junction protein, beta 1, 32kDa [Source:HGNC Symbol;Acc:4283] |
| Location: | chrX q13.1 |
| Node attribute: | substrate |
| Phosphorylation site |
| Position | PhosphoPeptide | Catalytic kinase | Source |
|---|---|---|---|
| S233 | PSRKGsGFGHR | PRKACA | HPRD |
| S229 | RSNPPsRKGSG | PKC_group | phosphoELM; RegPhos |
| S229 | RSNPPsRKGSG | PKCa | RegPhos |
| S233 | PSRKGsGFGHR | PKA_group | phosphoELM; RegPhos |
| S233 | PSRKGsGFGHR | PRKCA | HPRD |
| Y243 | RLSPEyKQNEI | PhosphoSitePlus | |
| S233 | PSRKGsGFGHR | PKC_group | phosphoELM; RegPhos |
| S233 | PSRKGsGFGHR | PKACa | RegPhos |
| S229 | RSNPPsRKGSG | PRKCA | HPRD |
| S233 | PSRKGsGFGHR | PKCa | RegPhos |
| S266 | DILRRsPGTGA | PhosphoSitePlus; HPRD | |
| Dephosphorylation site |
| CXB1_HUMAN do not have dephosphorylation site. |
| Mutation site |
| Ensembl ID | Variation | Source | Cancer name | Pubmed |
|---|---|---|---|---|
| ENSP00000354900 | W133* | COSMIC | Breast Cancer | 16959974 | ENSP00000354900 | W133X | BIOMART | Breast Cancer | 21930507, 21930502 | ENSP00000363134 | W133* | COSMIC | Breast Cancer | 16959974 | ENSP00000363141 | W133* | COSMIC | Breast Cancer | 16959974 |
| Differential expressed protein |
| CXB1_HUMAN is not differential expressed protein. |
| Hyperphosphorylation site |
| CXB1_HUMAN do not have hyperphosphorylation site. |
| Direct Interaction Pair |
| Source | Target | Relationship | Resource |
|---|---|---|---|
| KPCA_HUMAN | CXB1_HUMAN | kinase -> substrate | HPRD |
| Function Annotation |
| KEGG Pathway |
| CXB1_HUMAN is not in KEGG pathway. |
| Gene Ontology |
| GO ID | GO_Term | Evidence | Ontology |
|---|---|---|---|
| GO:0015868 | purine ribonucleotide transport | IEA | biological_process |
| GO:0051259 | protein oligomerization | IEA | biological_process |
| GO:0016264 | gap junction assembly | TAS | biological_process |
| GO:0042803 | protein homodimerization activity | IEA | molecular_function |
| GO:0016021 | integral to membrane | IEA | cellular_component |
| GO:0007267 | cell-cell signaling | TAS | biological_process |
| GO:0005243 | gap junction channel activity | IEA | molecular_function |
| GO:0005783 | endoplasmic reticulum | IEA | cellular_component |
| GO:0007399 | nervous system development | TAS | biological_process |
| GO:0007154 | cell communication | IEA | biological_process |
| GO:0005737 | cytoplasm | IEA | cellular_component |
| GO:0016044 | cellular membrane organization | TAS | biological_process |
| GO:0005922 | connexon complex | IEA | cellular_component |
| GO:0005886 | plasma membrane | IEA | cellular_component |
| GO:0005789 | endoplasmic reticulum membrane | TAS | cellular_component |
| GO:0005921 | gap junction | IEA | cellular_component |
| GO:0006810 | transport | TAS | biological_process |