Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:CP8B1_HUMAN
Description:cytochrome P450, family 8, subfamily B, polypeptide 1 [Source:HGNC Symbol;Acc:2653]
Location:chr3 p22.1
Node attribute:gene

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
S369YTLKMsSGQEYp450PhosphoSitePlus
Y182LFTAGyLSLFGPhosphoSitePlus
T62LKRMRtKHGDVp450PhosphoSitePlus
S326LETKQsFAFKLp450PhosphoSitePlus
T78GGQYFtFVMDPp450PhosphoSitePlus
T347SVVEEtLRLRAp450PhosphoSitePlus
T69HGDVFtVQLGGp450PhosphoSitePlus
S269EQGVPsAMQDKPhosphoSitePlus
Y76QLGGQyFTFVMp450PhosphoSitePlus
S127MIHSAsTKHLRPhosphoSitePlus; HPRD
S370TLKMSsGQEYLp450PhosphoSitePlus

Dephosphorylation site
CP8B1_HUMAN do not have dephosphorylation site.

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000318867G332SCOSMICOvarian Cancer21720365
ENSP00000318867R26*COSMICOvarian Cancer21720365

Differential expressed protein
CP8B1_HUMAN is not differential expressed protein.

Hyperphosphorylation site
CP8B1_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
HNF4A_HUMANCP8B1_HUMANTF -> target geneTRANSFAC

Function Annotation
KEGG Pathway
CP8B1_HUMAN is not in KEGG pathway.

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0009055electron carrier activityIEAmolecular_function
GO:0016021integral to membraneIEAcellular_component
GO:0008397sterol 12-alpha-hydroxylase activityTASmolecular_function
GO:0005789endoplasmic reticulum membraneTAScellular_component
GO:0006805xenobiotic metabolic processTASbiological_process
GO:0005506iron ion bindingIEAmolecular_function
GO:0020037heme bindingIEAmolecular_function
GO:0044281small molecule metabolic processTASbiological_process
GO:00337787alpha-hydroxycholest-4-en-3-one 12alpha-hydroxylaIEAmolecular_function
GO:0016705oxidoreductase activity, acting on paired donors, IEAmolecular_function
GO:0055114oxidation-reduction processIEAbiological_process
GO:0008206bile acid metabolic processTASbiological_process
GO:0006699bile acid biosynthetic processTASbiological_process
GO:0019825oxygen bindingTASmolecular_function


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