Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:CP1A1_HUMAN
Description:cytochrome P450, family 1, subfamily A, polypeptide 1 [Source:HGNC Symbol;Acc:2595]
Location:chr15 q24.1
Node attribute:gene

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
S360RRPRLsDRSHLHPRD; phosphoELM; SysPTM
S360RRPRLsDRSHLp450PhosphoSitePlus; SysPTM
Y270MVKEHyKTFEKp450PhosphoSitePlus
S247YLPNPsLNAFKp450PhosphoSitePlus

Dephosphorylation site
CP1A1_HUMAN do not have dephosphorylation site.

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000378488D436HCOSMICOvarian Cancer20826764
ENSP00000378488Y158XBIOMARTBreast Cancer21930507, 21930502
ENSP00000378488R98WCOSMICPancreatic Cancer
ENSP00000378488R477WCOSMICBreast Cancer16959974
ENSP00000378488Q507KCOSMICOvarian Cancer21720365
ENSP00000378488E176KCOSMICSkin Cancer21984974
ENSP00000378488Y158*COSMICBreast Cancer16959974
ENSP00000378488R477WSjoblom2006Breast Cancer16959974

Differential expressed protein
CP1A1_HUMAN is not differential expressed protein.

Hyperphosphorylation site
CP1A1_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
AHR_HUMANCP1A1_HUMANTF -> target geneTRANSFAC

Function Annotation
KEGG Pathway
CP1A1_HUMAN is not in KEGG pathway.

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0019899enzyme bindingIEAmolecular_function
GO:0006778porphyrin-containing compound metabolic processIEAbiological_process
GO:0018894dibenzo-p-dioxin metabolic processIEAbiological_process
GO:0016711flavonoid 3'-monooxygenase activityIEAmolecular_function
GO:0046483heterocycle metabolic processIEAbiological_process
GO:0005789endoplasmic reticulum membraneTAScellular_component
GO:0009615response to virusIEAbiological_process
GO:00429049-cis-retinoic acid biosynthetic processIEAbiological_process
GO:0055093response to hyperoxiaIEAbiological_process
GO:0055114oxidation-reduction processIDAbiological_process
GO:0016491oxidoreductase activityIEAmolecular_function
GO:0033189response to vitamin AIEAbiological_process
GO:0009611response to woundingIEAbiological_process
GO:0070330aromatase activityIEAmolecular_function
GO:0001889liver developmentIEAbiological_process
GO:0003824catalytic activityIEAmolecular_function
GO:0009055electron carrier activityIEAmolecular_function
GO:0014070response to organic cyclic compoundIEAbiological_process
GO:0009635response to herbicideIEAbiological_process
GO:0009404toxin metabolic processIEAbiological_process
GO:0016491oxidoreductase activityIDAmolecular_function
GO:0009308amine metabolic processIEAbiological_process
GO:0006950response to stressIEAbiological_process
GO:0009804coumarin metabolic processIEAbiological_process
GO:0032094response to foodIEAbiological_process
GO:0016705oxidoreductase activity, acting on paired donors, IEAmolecular_function
GO:0044255cellular lipid metabolic processTASbiological_process
GO:0006805xenobiotic metabolic processTASbiological_process
GO:0019341dibenzo-p-dioxin catabolic processIEAbiological_process
GO:0050665hydrogen peroxide biosynthetic processIEAbiological_process
GO:0001666response to hypoxiaIEAbiological_process
GO:0042359vitamin D metabolic processICbiological_process
GO:0005737cytoplasmIEAcellular_component
GO:0032496response to lipopolysaccharideIEAbiological_process
GO:0016679oxidoreductase activity, acting on diphenols and rIEAmolecular_function
GO:0016712oxidoreductase activity, acting on paired donors, IEAmolecular_function
GO:0044281small molecule metabolic processTASbiological_process
GO:0045750positive regulation of S phase of mitotic cell cycIEAbiological_process
GO:0009812flavonoid metabolic processIEAbiological_process
GO:0048565digestive tract developmentIEAbiological_process
GO:0043231intracellular membrane-bounded organelleIEAcellular_component
GO:0005506iron ion bindingIEAmolecular_function
GO:0010041response to iron(III) ionIEAbiological_process
GO:0010033response to organic substanceIEAbiological_process
GO:0032451demethylase activityIEAmolecular_function
GO:0043010camera-type eye developmentIEAbiological_process
GO:0009792embryo development ending in birth or egg hatchingIEAbiological_process
GO:0070365hepatocyte differentiationIEAbiological_process
GO:0019825oxygen bindingTASmolecular_function
GO:0070576vitamin D 24-hydroxylase activityIDAmolecular_function
GO:0032502developmental processIEAbiological_process
GO:0007568agingIEAbiological_process
GO:0004497monooxygenase activityIEAmolecular_function
GO:0008283cell proliferationIEAbiological_process
GO:0008395steroid hydroxylase activityIEAmolecular_function
GO:0042493response to drugIEAbiological_process
GO:0009636response to toxinIEAbiological_process
GO:0017144drug metabolic processIDAbiological_process
GO:0005515protein bindingIEAmolecular_function
GO:0070988demethylationIEAbiological_process
GO:0046685response to arsenic-containing substanceIEAbiological_process
GO:0060137maternal process involved in parturitionIEAbiological_process
GO:0020037heme bindingIEAmolecular_function
GO:0009624response to nematodeIEAbiological_process
GO:0005739mitochondrionIEAcellular_component
GO:0017143insecticide metabolic processIEAbiological_process
GO:0046677response to antibioticIEAbiological_process