| UniProt/SwissProt ID: | CO7A1_HUMAN |
| Description: | collagen, type VII, alpha 1 [Source:HGNC Symbol;Acc:2214] |
| Location: | chr3 p21.31 |
| Node attribute: | gene |
|
| Position | PhosphoPeptide | Catalytic kinase | Source |
|---|
| Y35 | TCTRLyAADIV | | PhosphoSitePlus |
| T703 | SSSSVtITWTR | fn3 | PhosphoSitePlus |
| T691 | LGPVRtVHVTQ | fn3 | PhosphoSitePlus |
| S202 | FVNDFsILRTL | VWA | PhosphoSitePlus |
| S47 | LLDGSsSIGRS | VWA | PhosphoSitePlus |
| T117 | YKGGNtRTGAA | VWA | PhosphoSitePlus |
| T695 | RTVHVtQASSS | fn3 | PhosphoSitePlus |
| S402 | TLFGRsVGPAT | fn3 | PhosphoSitePlus |
| S1686 | DGRNGsPGSSG | Collagen | PhosphoSitePlus |
| S1690 | GSPGSsGPKGD | Collagen | PhosphoSitePlus |
|
CO7A1_HUMAN do not have dephosphorylation site.
|
|
| Ensembl ID | Variation | Source | Cancer name | Pubmed |
|---|
| ENSP00000332371 | K1769M | COSMIC | Head and Neck Cancer | 21798893 |
ENSP00000332371 | S2235L | COSMIC | Skin Cancer | 21984974 | ENSP00000412569 | T1916I | BIOMART | Breast Cancer | 21930507, 21930502 | ENSP00000332371 | P1774S | COSMIC | Skin Cancer | 21984974 | ENSP00000332371 | R1366W | HPI, COSMIC | Breast Cancer | 9375848 16959974 | ENSP00000332371 | R1366W | Sjoblom2006 | Breast Cancer | 16959974, 9375848 | ENSP00000332371 | A2592T | COSMIC | Ovarian Cancer | 21720365 | ENSP00000332371 | T119P | Sjoblom2006, COSMIC, HPI | Breast Cancer | 16959974, 9375848, 9375848, 16959974, 9375848 16959974 | ENSP00000332371 | P2384S | COSMIC | Melanoma | 21499247 | ENSP00000332371 | M1192I | COSMIC | Head and Neck Cancer | 21798893 | ENSP00000332371 | T1948I | BIOMART | Breast Cancer | 21930507, 21930502 | ENSP00000332371 | S766F | COSMIC | Skin Cancer | 21984974 | ENSP00000332371 | E1466D | BIOMART | Pancreatic Cancer | 21930507, 21930502 | ENSP00000332371 | Q1255H | COSMIC | Ovarian Cancer | 21720365 | ENSP00000332371 | P1364T | Sjoblom2006, COSMIC, HPI | Breast Cancer | 16959974, 9375848, 9375848, 16959974, 9375848 16959974 | ENSP00000332371 | G2351A | COSMIC | Ovarian Cancer | 21720365 |
|
| CO7A1_HUMAN is not differential expressed protein. |
|
| CO7A1_HUMAN do not have hyperphosphorylation site. |
|
CO7A1_HUMAN is not in KEGG pathway.
|
|
| GO ID | GO_Term | Evidence | Ontology |
|---|
| GO:0005604 | basement membrane | IEA | cellular_component |
| GO:0031012 | extracellular matrix | ISS | cellular_component |
| GO:0005590 | collagen type VII | TAS | cellular_component |
| GO:0005515 | protein binding | IPI | molecular_function |
| GO:0004867 | serine-type endopeptidase inhibitor activity | IEA | molecular_function |
| GO:0007155 | cell adhesion | IEA | biological_process |
| GO:0030198 | extracellular matrix organization | TAS | biological_process |
| GO:0008544 | epidermis development | TAS | biological_process |
| GO:0005788 | endoplasmic reticulum lumen | TAS | cellular_component |
| GO:0005576 | extracellular region | TAS | cellular_component |
|
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