| UniProt/SwissProt ID: | CDK19_HUMAN |
| Description: | cyclin-dependent kinase 19 [Source:HGNC Symbol;Acc:19338] |
| Location: | chr6 q21 |
| Node attribute: | kinase |
| Phosphorylation site |
| Position | PhosphoPeptide | Catalytic kinase | Source |
|---|---|---|---|
| T286 | KDFRRtTYANS | HPRD | |
| S449 | PSGANsGGPVM | PhosphoSitePlus; HPRD | |
| T31 | KVGRGtYGHVY | Pkinase | PhosphoSitePlus |
| S292 | TYANSsLIKYM | HPRD | |
| Y296 | SSLIKyMEKHK | HPRD | |
| Dephosphorylation site |
| CDK19_HUMAN do not have dephosphorylation site. |
| Mutation site |
| Ensembl ID | Variation | Source | Cancer name | Pubmed |
|---|---|---|---|---|
| ENSP00000317665 | Q399H | BIOMART | Breast Cancer | 21930507, 21930502 | ENSP00000357907 | Q459H | BIOMART | Breast Cancer | 21930507, 21930502 | ENSP00000357907 | G175S | Greenman2007 | Skin Cancer | 17344846, 18428421 |
| Differential expressed protein |
| CDK19_HUMAN is not differential expressed protein. |
| Hyperphosphorylation site |
| CDK19_HUMAN do not have hyperphosphorylation site. |
| Direct Interaction Pair |
| Source | Target | Relationship | Resource |
|---|---|---|---|
| CDK19_HUMAN | EIF3F_HUMAN | kinase -> substrate | HPRD; RegPhos |
| Function Annotation |
| KEGG Pathway |
| CDK19_HUMAN is not in KEGG pathway. |
| Gene Ontology |
| GO ID | GO_Term | Evidence | Ontology |
|---|---|---|---|
| GO:0004674 | protein serine/threonine kinase activity | IEA | molecular_function |
| GO:0005524 | ATP binding | IEA | molecular_function |
| GO:0004672 | protein kinase activity | IEA | molecular_function |
| GO:0004693 | cyclin-dependent protein kinase activity | IEA | molecular_function |
| GO:0006468 | protein phosphorylation | IEA | biological_process |
| GO:0051301 | cell division | IEA | biological_process |
| GO:0004713 | protein tyrosine kinase activity | IEA | molecular_function |
| GO:0016772 | transferase activity, transferring phosphorus-cont | IEA | molecular_function |