Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:CCG2_HUMAN
Description:calcium channel, voltage-dependent, gamma subunit 2 [Source:HGNC Symbol;Acc:1406]
Location:chr22 q12.3
Node attribute:substrate

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
S253HSRDAsPVGIKRegPhos
Y229TRIPSyRYRYQPhosphoSitePlus
S228ITRIPsYRYRYPhosphoSitePlus
T321ANRRTtPVPKACaRegPhos
T321ANRRTtPRKACAHPRD
S249TEPSHsRDASPPhosphoSitePlus
T321ANRRTtPVRegPhos
Y271TEISMyTLSRDRegPhos
S125LCIAAsEFYKTPMP22_ClaudinPhosphoSitePlus

Dephosphorylation site
CCG2_HUMAN do not have dephosphorylation site.

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000300105A286TCOSMICSkin Cancer21984974
ENSP00000300105L120HBIOMARTPancreatic Cancer21930507, 21930502

Differential expressed protein
CCG2_HUMAN is not differential expressed protein.

Hyperphosphorylation site
CCG2_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
ZAGL2_HUMANCCG2_HUMANkinase -> substrateRegPhos
KPCA_HUMANCCG2_HUMANkinase -> substrateHPRD

Function Annotation
KEGG Pathway
KEGG IDPathway
hsa04260Cardiac muscle contraction
hsa05412Arrhythmogenic right ventricular cardiomyopathy (A
hsa05410Hypertrophic cardiomyopathy (HCM)
hsa04010MAPK signaling pathway
hsa05414Dilated cardiomyopathy

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0042391regulation of membrane potentialIEAbiological_process
GO:0060081membrane hyperpolarizationIEAbiological_process
GO:0050877neurological system processIEAbiological_process
GO:0016020membraneIEAcellular_component
GO:0035255ionotropic glutamate receptor bindingIEAmolecular_function
GO:0005891voltage-gated calcium channel complexIEAcellular_component
GO:0005245voltage-gated calcium channel activityIEAmolecular_function
GO:2000311regulation of alpha-amino-3-hydroxy-5-methyl-4-isoISSbiological_process
GO:0005515protein bindingIPImolecular_function
GO:0007268synaptic transmissionTASbiological_process
GO:0006810transportTASbiological_process
GO:0019226transmission of nerve impulseIEAbiological_process
GO:0032281alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropioniIEAcellular_component
GO:0051899membrane depolarizationIEAbiological_process
GO:0030666endocytic vesicle membraneTAScellular_component
GO:0051899membrane depolarizationTASbiological_process
GO:0005515protein bindingIEAmolecular_function
GO:0007528neuromuscular junction developmentIEAbiological_process
GO:2000311regulation of alpha-amino-3-hydroxy-5-methyl-4-isoIEAbiological_process
GO:0005886plasma membraneTAScellular_component
GO:0032281alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropioniISScellular_component